2. Gene
  3. GATAD2A - GATA zinc finger domain containing 2A Gene

GATAD2A - GATA zinc finger domain containing 2A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as p66alpha

Gene ID: 54815 | Gene type: protein coding

About GATAD2A

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:19,385,843-19,508,932 (from NCBI)

This gene has 13 transcripts (splice variants), 282 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 18.1), spleen (RPKM 10.8) and 25 other tissues.

Summary

Enables protein-macromolecule adaptor activity. Involved in negative regulation of transcription, DNA-templated. Located in nucleoplasm. Part of NuRD complex. [provided by Alliance of Genome Resources, Apr 2022]

GATAD2A Products(33)

mRNA Protein Name
NM_001300946.3 NP_001287875.1 transcriptional repressor p66-alpha isoform 1
NM_001359631.2 NP_001346560.1 transcriptional repressor p66-alpha isoform 3
NM_001384511.1 NP_001371440.1 transcriptional repressor p66-alpha isoform 1
NM_001384512.1 NP_001371441.1 transcriptional repressor p66-alpha isoform 1
NM_001384513.1 NP_001371442.1 transcriptional repressor p66-alpha isoform 1
NM_001384514.1 NP_001371443.1 transcriptional repressor p66-alpha isoform 1
NM_001384515.1 NP_001371444.1 transcriptional repressor p66-alpha isoform 1
NM_001384516.1 NP_001371445.1 transcriptional repressor p66-alpha isoform 1
NM_001384517.1 NP_001371446.1 transcriptional repressor p66-alpha isoform 1
NM_001384518.1 NP_001371447.1 transcriptional repressor p66-alpha isoform 1
NM_001384519.1 NP_001371448.1 transcriptional repressor p66-alpha isoform 1
NM_001384521.1 NP_001371450.1 transcriptional repressor p66-alpha isoform 1
NM_001384522.1 NP_001371451.1 transcriptional repressor p66-alpha isoform 1
NM_001384523.1 NP_001371452.1 transcriptional repressor p66-alpha isoform 1
NM_001384524.1 NP_001371453.1 transcriptional repressor p66-alpha isoform 1
NM_001384525.1 NP_001371454.1 transcriptional repressor p66-alpha isoform 1
NM_001384526.1 NP_001371455.1 transcriptional repressor p66-alpha isoform 1
NM_001384527.1 NP_001371456.1 transcriptional repressor p66-alpha isoform 1
NM_001384528.1 NP_001371457.1 transcriptional repressor p66-alpha isoform 1
NM_001384529.1 NP_001371458.1 transcriptional repressor p66-alpha isoform 2
NM_001384530.1 NP_001371459.1 transcriptional repressor p66-alpha isoform 2
NM_001384531.1 NP_001371460.1 transcriptional repressor p66-alpha isoform 2
NM_001384532.1 NP_001371461.1 transcriptional repressor p66-alpha isoform 2
NM_001384533.1 NP_001371462.1 transcriptional repressor p66-alpha isoform 2
NM_001384534.1 NP_001371463.1 transcriptional repressor p66-alpha isoform 3
NM_001384535.1 NP_001371464.1 transcriptional repressor p66-alpha isoform 3
NM_001384536.1 NP_001371465.1 transcriptional repressor p66-alpha isoform 3
NM_001384537.1 NP_001371466.1 transcriptional repressor p66-alpha isoform 4
NM_001384538.1 NP_001371467.1 transcriptional repressor p66-alpha isoform 5
NM_001384539.1 NP_001371468.1 transcriptional repressor p66-alpha isoform 6
NM_001384540.1 NP_001371469.1 transcriptional repressor p66-alpha isoform 7
NM_001384541.1 NP_001371470.1 transcriptional repressor p66-alpha isoform 7
NM_017660.5 NP_060130.3 transcriptional repressor p66-alpha isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12183469 GOA
enables protein-macromolecule adaptor activity IDA
IDA: Inferred from direct assay
12183469 GOA
Biological Process GO Annotation Evidence Reference Source
involved in chromatin remodeling IDA
IDA: Inferred from direct assay
9790534 GOA
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12183469 GOA
Cellular Component GO Annotation Evidence Reference Source
part of NuRD complex IDA
IDA: Inferred from direct assay
12183469 GOA
located in nucleus IDA
IDA: Inferred from direct assay
12183469 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcriptional repressor p66-alpha

GATA zinc finger domain-containing protein 2A

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P10326 Z-ATAD-FMK Inhibitor / Unkown
HY-RS05296 GATAD2A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GATAD2A RGD RGD:1310596
Felis catus GATAD2A VGNC VGNC:62477
Mus musculus GATAD2A MGD MGI:2384585
Bos taurus GATAD2A VGNC VGNC:29271
Canis familiaris GATAD2A VGNC VGNC:41126