ATG2B - autophagy related 2B Gene

Homo sapiens

Also known as BLTP4B; C14orf103

Gene ID: 55102 | Gene type: protein coding

About ATG2B

Cytogenetic location: 14q32.2 Genomic coordinates (GRCh38): 14:96,279,195-96,363,341 (from NCBI)

This gene has 7 transcripts (splice variants), 214 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 8.1), skin (RPKM 7.0) and 25 other tissues.

Summary

This gene encodes a protein required for Autophagy. The encoded protein is involved in autophagosome formation. A germline duplication of a region that includes this gene is associated with predisposition to myeloid malignancies. [provided by RefSeq, Jul 2016]

ATG2B Products(1)

mRNA	Protein	Name
NM_018036.7	NP_060506.6	autophagy-related protein 2 homolog B

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables lipid transfer activity	IDA IDA: Inferred from direct assay	31721365	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	20562859	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ATG2B Protein Structure

Chorein_N

ATG2_CAD

ATG_C

0
400
800
1200
1600
2078 a.a.

Protein Preferred Names

Protein Names

autophagy-related protein 2 homolog B

ATG2 autophagy related 2 homolog B

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01146	ATG2B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ATG2B	VGNC	VGNC:26255
Mus musculus	ATG2B	MGD	MGI:1923809
Canis familiaris	ATG2B	VGNC	VGNC:38222
Macaca mulatta	ATG2B	VGNC	VGNC:84310
Rattus norvegicus	ATG2B	RGD	RGD:1304878
Felis catus	ATG2B	VGNC	VGNC:60001

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