2. Gene
  3. ATG2B - autophagy related 2B Gene

ATG2B - autophagy related 2B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BLTP4B; C14orf103

Gene ID: 55102 | Gene type: protein coding

About ATG2B

Cytogenetic location: 14q32.2 Genomic coordinates (GRCh38): 14:96,279,195-96,363,341 (from NCBI)

This gene has 7 transcripts (splice variants), 214 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 8.1), skin (RPKM 7.0) and 25 other tissues.

Summary

This gene encodes a protein required for Autophagy. The encoded protein is involved in autophagosome formation. A germline duplication of a region that includes this gene is associated with predisposition to myeloid malignancies. [provided by RefSeq, Jul 2016]

ATG2B Products(1)

mRNA Protein Name
NM_018036.7 NP_060506.6 autophagy-related protein 2 homolog B

ATG2B Protein Structure

Chorein_N

Chorein_N: N-terminal region of Chorein or VPS13 (16 - 110)

ATG2_CAD

ATG2_CAD: Autophagy-related protein 2 CAD motif (1295 - 1361)

ATG_C

ATG_C: Autophagy-related protein C terminal domain (1980 - 2074)

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  • 2078 a.a.
Protein Preferred Names Protein Names

autophagy-related protein 2 homolog B

ATG2 autophagy related 2 homolog B

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01146 ATG2B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ATG2B VGNC VGNC:26255
Mus musculus ATG2B MGD MGI:1923809
Canis familiaris ATG2B VGNC VGNC:38222
Macaca mulatta ATG2B VGNC VGNC:84310
Rattus norvegicus ATG2B RGD RGD:1304878
Felis catus ATG2B VGNC VGNC:60001