2. Gene
  3. RESF1 - retroelement silencing factor 1 Gene

RESF1 - retroelement silencing factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as GET; UTA2-1; C12orf35; KIAA1551

Gene ID: 55196 | Gene type: protein coding

About RESF1

Cytogenetic location: 12p11.21 Genomic coordinates (GRCh38): 12:31,959,415-31,993,107 (from NCBI)

This gene has 8 transcripts (splice variants) and 120 orthologues. Broad expression in lymph node (RPKM 38.5), ovary (RPKM 35.0) and 24 other tissues.

Summary

Predicted to enable histone binding activity and Histone Methyltransferase binding activity. Predicted to be involved in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate and positive regulation of DNA methylation-dependent heterochromatin assembly. Predicted to act upstream of or within response to bacterium. Predicted to be located in nucleus. Predicted to colocalize with gamma-tubulin complex. [provided by Alliance of Genome Resources, Apr 2022]

RESF1 Products(1)

mRNA Protein Name
NM_018169.4 NP_060639.4 retroelement silencing factor 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RESF1 Protein Structure

DUF4617

DUF4617: Domain of unknown function (DUF4617) (669 - 1739)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1747 a.a.
Protein Preferred Names Protein Names

retroelement silencing factor 1

gonad expressed transcript

RESF1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
RESF1 Q9HCM1 KRT36 Homo sapiens O76013-2
Y2H Prey Pooling
32296183
Intra
RESF1 Q9HCM1 KRT36 Homo sapiens O76013-2
Y2H Array
32296183
Intra
RESF1 Q9HCM1 KRT86 Homo sapiens O43790
Y2H Array
32296183
Intra
RESF1 Q9HCM1 KRT86 Homo sapiens O43790
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11851 RESF1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RESF1 RGD RGD:1309621
Bos taurus RESF1 VGNC VGNC:30572
Macaca mulatta RESF1 VGNC VGNC:76823
Felis catus RESF1 VGNC VGNC:64576
Mus musculus RESF1 MGD MGI:1914496
Canis familiaris RESF1 VGNC VGNC:42371