RAVER2 - ribonucleoprotein, PTB binding 2 Gene

Homo sapiens

Gene ID: 55225 | Gene type: protein coding

About RAVER2

Cytogenetic location: 1p31.3 Genomic coordinates (GRCh38): 1:64,745,075-64,833,232 (from NCBI)

This gene has 3 transcripts (splice variants), 222 orthologues and 7 paralogues. Ubiquitous expression in small intestine (RPKM 13.3), colon (RPKM 12.9) and 24 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RAVER2 Products(2)

mRNA	Protein	Name
NM_001366165.2	NP_001353094.1	ribonucleoprotein PTB-binding 2 isoform 1
NM_018211.4	NP_060681.2	ribonucleoprotein PTB-binding 2 isoform 2

RAVER2 Protein Structure

RRM_1

0
200
400
600
691 a.a.

Protein Preferred Names

Protein Names

ribonucleoprotein PTB-binding 2

protein raver-2

RAVER2 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P82092	RAVER2 Antibody (YA1837)	WB, IHC-F, IHC-P, ICC/IF, IP	Human

Related Diseases

Diseases

Alias

Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant

ADLD	Adult-Onset Autosomal Dominant Demyelinating Leukodystrophy
Leukodystrophy, Adult-Onset, Autosomal Dominant	Adult-Onset Autosomal Dominant Leukodystrophy
Autosomal Dominant Leukodystrophy With Autonomic Disease	Autosomal Dominant Adult-Onset Demyelinating Leukodystrophy
Multiple Sclerosis-Like Disorder	Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type, Formerly
Autosomal-Dominant Or Late-Onset Type Pelizaeus-Merzbacher Disease	Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type
Adult-Onset Autosomal Dominant Leukodystrophy With Autonomic Symptoms	Lmnb1-Related Adult-Onset Autosomal Dominant Leukodystrophy
Leukodystrophy, Demyelinating, Autosomal Dominant, Adult-Onset	Pelizaeus-Merzbacher Disease Autosomal Dominant
Pelizaeus-Merzbacher Disease Late-Onset Type	Adult Onset Autosomal Dominant Leukodystrophy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11710	RAVER2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	RAVER2	VGNC	VGNC:33766
Mus musculus	RAVER2	MGD	MGI:2443623
Felis catus	RAVER2	VGNC	VGNC:64513
Macaca mulatta	RAVER2	VGNC	VGNC:76536
Canis familiaris	RAVER2	VGNC	VGNC:45387
Rattus norvegicus	RAVER2	RGD	RGD:1307610

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