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55296

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P700383
    PEX19 Protein, Human (GST)

    PEX19; peroxisomal biogenesis factor 19; peroxisomal farnesylated protein , PXF; D1S2223E; HK33; housekeeping gene; 33kD; PMP1; PMPI; PXMP1; peroxin-19; housekeeping gene, 33kD; 33 kDa housekeeping protein; peroxisomal farnesylated protein; PXF; FLJ55296

    		 Human E. coli
    PEX19 protein is pivotal in early peroxisomal biogenesis, acting as a cytosolic chaperone and import receptor for peroxisomal membrane proteins (PMPs). It binds to and stabilizes newly synthesized PMPs in the cytoplasm, particularly their hydrophobic domains. PEX19 targets PMPs to the peroxisome membrane by associating with integral membrane protein PEX3. Engaging in diverse interactions with peroxisomal membrane proteins and other components, PEX19 facilitates peroxisomal assembly. Additionally, it contributes to nuclear exclusion of CDKN2A, preventing TP53 degradation by MDM2 and interacting with tumor suppressor CDKN2A/p19ARF in intricate cellular processes. PEX19 Protein, Human (GST) is the recombinant human-derived PEX19 protein, expressed by E. coli, with N-GST labeled tag. The total length of PEX19 Protein, Human (GST) is 295 a.a., with molecular weight of 59.3 kDa.

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