2. Gene
  3. UGGT2 - UDP-glucose glycoprotein glucosyltransferase 2 Gene

UGGT2 - UDP-glucose glycoprotein glucosyltransferase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as UGT2; HUGT2; UGCGL2

Gene ID: 55757 | Gene type: protein coding

About UGGT2

Cytogenetic location: 13q32.1 Genomic coordinates (GRCh38): 13:95,801,580-96,053,401 (from NCBI)

This gene has 12 transcripts (splice variants), 212 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 5.5), testis (RPKM 4.6) and 25 other tissues.

Summary

UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]

UGGT2 Products(1)

mRNA Protein Name
NM_020121.4 NP_064506.3 UDP-glucose:glycoprotein glucosyltransferase 2 precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23349634 GOA
Cellular Component GO Annotation Evidence Reference Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
23349634 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UGGT2 Protein Structure

UDP-g_GGTase

UDP-g_GGTase: UDP-glucose:Glycoprotein Glucosyltransferase (922 - 1127)

Glyco_transf_8

Glyco_transf_8: Glycosyl transferase family 8 (1242 - 1458)

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  • 1516 a.a.
Protein Preferred Names Protein Names

UDP-glucose:glycoprotein glucosyltransferase 2

UDP-Glc:glycoprotein glucosyltransferase 2

UGGT2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
UGGT2 Q9NYU1 HSPA5 Homo sapiens P11021
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15424 UGGT2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris UGGT2 VGNC VGNC:48119
Mus musculus UGGT2 MGD MGI:1913685
Felis catus UGGT2 VGNC VGNC:66807
Macaca mulatta UGGT2 VGNC VGNC:78982
Bos taurus UGGT2 VGNC VGNC:36650
Rattus norvegicus UGGT2 RGD RGD:1563520