2. Gene
  3. EAPP - E2F associated phosphoprotein Gene

EAPP - E2F associated phosphoprotein Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as BM036; C14orf11

Gene ID: 55837 | Gene type: protein coding

About EAPP

Cytogenetic location: 14q13.1 Genomic coordinates (GRCh38): 14:34,515,938-34,539,701 (from NCBI)

This gene has 4 transcripts (splice variants) and 215 orthologues. Ubiquitous expression in bone marrow (RPKM 22.0), colon (RPKM 18.0) and 25 other tissues.

Summary

This gene encodes a phosphoprotein that interacts with several members of the E2F family of proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except during mitosis. It functions to modulate E2F-regulated transcription and stimulate proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

EAPP Products(2)

mRNA Protein Name
NM_001318916.2 NP_001305845.1 E2F-associated phosphoprotein isoform 2
NM_018453.4 NP_060923.2 E2F-associated phosphoprotein isoform 1

EAPP Protein Structure

Eapp_C

Eapp_C: E2F-associated phosphoprotein (138 - 283)

  • 0
  • 100
  • 200
  • 285 a.a.
Protein Preferred Names Protein Names

E2F-associated phosphoprotein

Related Diseases

Diseases Alias
Holoprosencephaly 8

HPE8

Holoprosencephaly-8
Spastic Hemiplegia

Spastic Hemiplegic Cerebral Palsy

Hemiplegic Cerebral Palsy

Congenital Hemiplegia

Hemiplegic Infantile Cerebral Palsy

Cerebral Palsy Spastic Hemiplegic

Spastic Hemiplegia Cerebral Palsy

Hemiplegia, Spastic
Holoprosencephaly

Holoprosencephaly Sequence

Hpe

Hpe - [Holoprosencephaly]
Cartilage Cancer

Chondrogenic Neoplasm
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-149209 LL-K8-22 99.76% Unkown
HY-RS04121 EAPP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus EAPP MGD MGI:1913516
Macaca mulatta EAPP VGNC VGNC:108295
Felis catus EAPP VGNC VGNC:80981
Rattus norvegicus EAPP RGD RGD:1309624
Bos taurus EAPP VGNC VGNC:28296