PRM1 - protamine 1 Gene

Homo sapiens

Also known as P1; CT94.1

Gene ID: 5619 | Gene type: protein coding

About PRM1

Cytogenetic location: 16p13.13 Genomic coordinates (GRCh38): 16:11,280,841-11,281,330 (from NCBI)

This gene has 1 transcript (splice variant) and 17 orthologues. Restricted expression toward testis (RPKM 2212.7).

Summary

Predicted to enable DNA binding activity. Predicted to be involved in DNA packaging. Predicted to act upstream of or within nucleus organization and spermatid development. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PRM1 Products(1)

mRNA	Protein	Name
NM_002761.3	NP_002752.1	sperm protamine P1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRM1 Protein Structure

Protamine_P1

0
51 a.a.

Protein Preferred Names

Protein Names

sperm protamine P1

cancer/testis antigen family 94, member 1

PRM1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PRM1	P04553	CLK2	Homo sapiens	P49760	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Male Infertility

Infertility, Male	Infertility Male
Male Sterility	Absolute Infertility

Infertility

Varicocele

Scrotal Varices	Varicoceles
Varicocele Of Scrotum	Scrotal Varicocele

Spermatogenic Failure

Azoospermia	Spgf
Spermatogenic Failure, Susceptibility To	Absent Sperm
Aspermatogenesis	Infertility Due To Azoospermia
Hypospermatogenesis	Azoospermatism

Nickel Allergic Contact Dermatitis

Allergic Contact Dermatitis To Ni

Pelvic Varices

Varix Of Pelvis

Pelvic Varicose Vein

Oligoasthenoteratozoospermia

Oat	Oligoasthenoteratospermia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11164	PRM1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	PRM1	MGD	MGI:97765
Rattus norvegicus	PRM1	RGD	RGD:1583873
Others	PRM1	NCBI

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