2. Gene
  3. ASCL3 - achaete-scute family bHLH transcription factor 3 Gene

ASCL3 - achaete-scute family bHLH transcription factor 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SGN1; HASH3; bHLHa42

Gene ID: 56676 | Gene type: protein coding

About ASCL3

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:8,937,578-8,943,016 (from NCBI)

This gene has 1 transcript (splice variant), 169 orthologues and 4 paralogues. Biased expression in salivary gland (RPKM 1.2) and testis (RPKM 0.1).

Summary

Basic helix-loop-helix transcription factors, such as ASCL3, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]

ASCL3 Products(1)

mRNA Protein Name
NM_020646.3 NP_065697.1 achaete-scute homolog 3
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ASCL3 Protein Structure

HLH

HLH: Helix-loop-helix DNA-binding domain (97 - 146)

  • 0
  • 100
  • 181 a.a.
Protein Preferred Names Protein Names

achaete-scute homolog 3

achaete-scute complex homolog 3

Related Diseases

Diseases Alias
Ascaris Lumbricoides Infection

Ascariasis

Ascaris Lumbricoides Infection, Susceptibility To

Ascariasis, Susceptibility To

Ascariasis - Roundworm

Infection Due To Ascaris Lumbricoides

Ascaridiasis

Roundworm Infection

Ascaridia

Ascaridiosis

Ascaridosis

Ascariosis

Ascaris

Ascaris Lumbricoides Infestation

Ascaris Infection

Infection By Ascaridia
Anisakiasis

Infection By Anisakis Larva

Anisakis Infection

Pseudoterranova Infection

Anisakiasis Due To Anisakis Simplex

Anisakiasis Due To Pseudoterranova Decipiens

Anisakis Infestation

Infection Due To Anisakis Larvae
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01080 ASCL3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ASCL3 VGNC VGNC:54856
Canis familiaris ASCL3 VGNC VGNC:38175
Mus musculus ASCL3 MGD MGI:1928820
Felis catus ASCL3 VGNC VGNC:68333
Rattus norvegicus ASCL3 RGD RGD:621631
Macaca mulatta ASCL3 VGNC VGNC:70031