NLN - neurolysin Gene

Homo sapiens

Also known as MEP; MOP; AGTBP; EP24.16

Gene ID: 57486 | Gene type: protein coding

About NLN

Cytogenetic location: 5q12.3 Genomic coordinates (GRCh38): 5:65,722,205-65,829,283 (from NCBI)

This gene has 10 transcripts (splice variants), 197 orthologues and 2 paralogues. Ubiquitous expression in liver (RPKM 3.9), brain (RPKM 3.5) and 25 other tissues.

Summary

This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.[provided by RefSeq, Jun 2010]

NLN Products(1)

mRNA	Protein	Name
NM_020726.5	NP_065777.1	neurolysin, mitochondrial

NLN Protein Structure

Peptidase_M3

0
200
400
600
704 a.a.

Protein Preferred Names

Protein Names

neurolysin, mitochondrial

angiotensin binding protein

Recombinant NLN Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75938	Neurolysin Protein, Human (His)	Q9BYT8 (S38-P704)	≥95%

Related Diseases

Diseases

Alias

Senile Ectropion

Involutional Ectropion

Astigmatism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09345	NLN Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	NLN	RGD	RGD:621518
Macaca mulatta	NLN	VGNC	VGNC:75183
Felis catus	NLN	VGNC	VGNC:63825
Mus musculus	NLN	MGD	MGI:1923055
Bos taurus	NLN	VGNC	VGNC:97293
Canis familiaris	NLN	VGNC	VGNC:43842
Others	NLN	NCBI

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