2. Gene
  3. SHTN1 - shootin 1 Gene

SHTN1 - shootin 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as KIAA1598; shootin-1

Gene ID: 57698 | Gene type: protein coding

About SHTN1

Cytogenetic location: 10q25.3 Genomic coordinates (GRCh38): 10:116,881,477-117,126,586 (from NCBI)

This gene has 7 transcripts (splice variants), 206 orthologues, 18 paralogues and is associated with 68 phenotypes. Ubiquitous expression in brain (RPKM 8.9), thyroid (RPKM 3.4) and 23 other tissues.

Summary

Enables identical protein binding activity. Involved in positive regulation of neuron migration. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SHTN1 Products(5)

mRNA Protein Name
NM_001127211.3 NP_001120683.1 shootin-1 isoform a
NM_001258298.2 NP_001245227.1 shootin-1 isoform c
NM_001258299.2 NP_001245228.1 shootin-1 isoform d
NM_001258300.1 NP_001245229.1 shootin-1 isoform e
NM_018330.7 NP_060800.2 shootin-1 isoform b
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of neuron migration IDA
IDA: Inferred from direct assay
23864681 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
25468996 GOA
located in microtubule IDA
IDA: Inferred from direct assay
23864681 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

shootin-1

shootin1

Related Diseases

Diseases Alias
Colorectal Cancer, Hereditary Nonpolyposis, Type 2

HNPCC2

Fcc2

Coca2

Hereditary Nonpolyposis Colorectal Cancer Type 2

Colon Cancer, Familial Nonpolyposis, Type 2

Familial Nonpolyposis Colon Cancer Type 2

Hereditary Non-Polyposis Colorectal Cancer 2

Cancer, Colorectal, Nonpolyposis, Hereditary, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12888 SHTN1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris SHTN1 VGNC VGNC:46160
Macaca mulatta SHTN1 VGNC VGNC:77333
Felis catus SHTN1 VGNC VGNC:65136
Rattus norvegicus SHTN1 RGD RGD:1311558
Mus musculus SHTN1 MGD MGI:1918903
Bos taurus SHTN1 VGNC VGNC:34611