2. Gene
  3. Crlf2 - cytokine receptor-like factor 2 Gene

Crlf2 - cytokine receptor-like factor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CRLM2; Ly114; Tpte2; Tslpr

Gene ID: 57914 | Gene type: protein coding

About Crlf2

Summary

Predicted to enable cytokine activity; cytokine binding activity; and cytokine receptor activity. Acts upstream of or within inflammatory response. Located in external side of plasma membrane. Is expressed in rib. Orthologous to human CRLF2 (cytokine receptor like factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Crlf2 Products(3)

mRNA Protein Name
NM_001164735.1 NP_001158207.1 cytokine receptor-like factor 2 isoform 1 precursor
NM_001310694.1 NP_001297623.1 cytokine receptor-like factor 2 isoform 3
NM_016715.4 NP_057924.3 cytokine receptor-like factor 2 isoform 2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
24632570 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within T-helper 2 cell cytokine production IDA
IDA: Inferred from direct assay
16142237 MGI
acts upstream of or within immunoglobulin production involved in immunoglobulin-mediated immune response IDA
IDA: Inferred from direct assay
16142237 MGI
acts upstream of or within inflammatory response IMP
IMP: Inferred from mutant phenotype
16142237 MGI
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
15488943 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytokine receptor-like factor 2

TSLP receptor

cytokine receptor-like molecule 2

lymphocyte antigen 114

thymic stromal lymphopoietin protein receptor

thymic stromal-derived lymphopoietin, receptor

transmembrane phosphoinositide 3-phosphatase and tensin homolog 2

type I cytokine rec

Recombinant Crlf2 Proteins

Cat. No. Product Name Accession Purity
HY-P70823 TSLPR Protein, Mouse (HEK293, Fc) AAH23788.1 (A20-L233) ≥95%
HY-P70989 TSLP R Protein, Mouse (HEK293, His) AAH23788.1 (A20-L233) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P990774 Verekitug Inhibitor 97.00% Phase 2
HY-P990767 Solrikitug Inhibitor 99.28% Phase 2
Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-151902 SJ988497 98.05% Unkown
HY-RS03187 CRLF2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crlf2 NCBI NCBI:64109
Macaca fascicularis Crlf2 NCBI NCBI:123571109