2. Gene
  3. Trem1 - triggering receptor expressed on myeloid cells 1 Gene

Trem1 - triggering receptor expressed on myeloid cells 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 58217 | Gene type: protein coding

About Trem1

Summary

Predicted to enable scaffold protein binding activity. Acts upstream of or within neutrophil chemotaxis; neutrophil extravasation; and neutrophil-mediated killing of gram-negative bacterium. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in bladder and renal vasculature. Human ortholog(s) of this gene implicated in Bacterial pneumonia; Bacterial sepsis; malaria; and myocardial infarction. Orthologous to human TREM1 (triggering receptor expressed on myeloid cells 1). [provided by Alliance of Genome Resources, Apr 2022]

Trem1 Products(2)

mRNA Protein Name
NM_001347399.1 NP_001334328.1 triggering receptor expressed on myeloid cells 1 isoform 2 precursor
NM_021406.5 NP_067381.1 triggering receptor expressed on myeloid cells 1 isoform 1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within chemokine production IGI
IGI: Inferred from genetic interaction
23241959 MGI
acts upstream of or within cytokine production IGI
IGI: Inferred from genetic interaction
23241959 MGI
acts upstream of or within cytokine production involved in immune response IGI
IGI: Inferred from genetic interaction
23241959 MGI
acts upstream of or within neutrophil chemotaxis IGI
IGI: Inferred from genetic interaction
23241959 MGI
acts upstream of or within neutrophil extravasation IGI
IGI: Inferred from genetic interaction
23241959 MGI
acts upstream of or within neutrophil migration IGI
IGI: Inferred from genetic interaction
23241959 MGI
acts upstream of or within neutrophil-mediated killing of gram-negative bacterium IGI
IGI: Inferred from genetic interaction
23241959 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

triggering receptor expressed on myeloid cells 1

triggering receptor expressed in monocytes 1

Recombinant Trem1 Proteins

Cat. No. Product Name Accession Purity
HY-P70716 TREM-1 Protein, Mouse (HEK293, His) Q9JKE2 (A21-S202) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-157122 VJDT 99.68% Unkown
HY-RS15002 TREM1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trem1 NCBI NCBI:54210