2. Gene
  3. SCPEP1 - serine carboxypeptidase 1 Gene

SCPEP1 - serine carboxypeptidase 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RISC; HSCP1

Gene ID: 59342 | Gene type: protein coding

About SCPEP1

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:56,978,131-57,006,768 (from NCBI)

This gene has 16 transcripts (splice variants), 212 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 64.9), adrenal (RPKM 63.4) and 24 other tissues.

Summary

Predicted to enable serine-type Carboxypeptidase activity. Predicted to be involved in negative regulation of blood pressure and retinoic acid metabolic process. Predicted to act upstream of or within blood vessel diameter maintenance. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

SCPEP1 Products(1)

mRNA Protein Name
NM_021626.3 NP_067639.1 retinoid-inducible serine carboxypeptidase precursor

SCPEP1 Protein Structure

Peptidase_S10

Peptidase_S10: Serine carboxypeptidase (35 - 448)

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  • 452 a.a.
Protein Preferred Names Protein Names

retinoid-inducible serine carboxypeptidase

serine carboxypeptidase 1 precursor protein

Recombinant SCPEP1 Proteins

Cat. No. Product Name Accession Purity
HY-P73675 RISC Protein, Human (HEK293, His) Q9HB40 (A27-E452) ≥95%

Related Diseases

Diseases Alias
Galactosialidosis

Goldberg Syndrome

Neuraminidase Deficiency With Beta-Galactosidase Deficiency

Ppca Deficiency

GSL

Lysosomal Protective Protein Deficiency

Cathepsin A Deficiency

Neuraminidase/Beta-Galactosidase Expression

Protective Protein/Cathepsin A Deficiency

Ngbe

Cathepsin A Deficiency Of

Lysosomal Protective Protein Deficiency Of

Deficiency Of Cathepsin A

Neuraminidase Beta-Galactosidase Deficiency

Protective Protein Cathepsin A Deficiency
Malignant Iris Melanoma

Malignant Melanoma Of Iris

Melanoma Of The Iris
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12560 SCPEP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SCPEP1 VGNC VGNC:64933
Rattus norvegicus SCPEP1 RGD RGD:620067
Canis familiaris SCPEP1 VGNC VGNC:55815
Mus musculus SCPEP1 MGD MGI:1921867
Macaca mulatta SCPEP1 VGNC VGNC:82232
Bos taurus SCPEP1 VGNC VGNC:34363
Others SCPEP1 NCBI