1. Gene
  2. CPLX3 - complexin 3 Gene

CPLX3 - complexin 3 Gene

Homo sapiens

Also known as CPXIII; CPX-III; Nbla11589

Gene ID: 594855 | Gene type: protein coding

About CPLX3

Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:74,826,627-74,831,802 (from NCBI)

This gene has 1 transcript (splice variant), 211 orthologues and 3 paralogues. Biased expression in prostate (RPKM 58.8), spleen (RPKM 33.7) and 3 other tissues.

Summary

Predicted to enable SNARE binding activity. Predicted to be involved in regulation of neurotransmitter secretion and synaptic vesicle exocytosis. Predicted to be located in plasma membrane and synapse. Predicted to be part of SNARE complex. Predicted to be active in photoreceptor ribbon synapse and terminal bouton. Predicted to be anchored component of presynaptic active zone membrane and anchored component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022]

CPLX3 Products(1)

mRNA Protein Name
NM_001030005.3 NP_001025176.1 complexin-3

CPLX3 Protein Structure

Synaphin

Synaphin: Synaphin protein (1 - 140)

  • 0
  • 100
  • 158 a.a.
Protein Preferred Names Protein Names

complexin-3

CPX III

Recombinant CPLX3 Proteins

Cat. No. Product Name Accession Purity
HY-P76848 CPLX3 Protein, Human (HEK293, His) Q8WVH0 (M1-K154) ≥95%

Related Diseases

Diseases Alias
Chromosome 15q24 Deletion Syndrome

15q24 Microdeletion Syndrome

Del(15)(Q24)

Monosomy 15q24

15q24 Microdeletion

15q24 Deletion

Interstitial Deletion Of Chromosome 15q24

Noonan Syndrome 1

Noonan Syndrome

NS1

Male Turner Syndrome

Female Pseudo-Turner Syndrome

Turner Phenotype With Normal Karyotype

Noonan Syndrome With Pigmented Villonodular Synovitis

Turner'S Phenotype, Karyotype Normal

Familial Turner Syndrome

Noonan'S Syndrome

Noonan-Ehmke Syndrome

Ns

Pseudo-Ullrich-Turner Syndrome

Turner Syndrome In Female With X Chromosome

Turner-Like Syndrome

Ullrich-Noonan Syndrome

Noonan-Like/Multiple Giant Cell Lesion Syndrome

Noonan Syndrome-Like Disorder With Multiple Giant Cell Lesions

Pterygium Colli Syndrome

Noonan Syndrome, Type 1

Turner Syndrome, Male

Chromosome 22q11.2 Deletion Syndrome, Distal

22q11.2 Deletion Syndrome

Autosomal Dominant Opitz G/Bbb Syndrome

Catch22

Cayler Cardiofacial Syndrome

Conotruncal Anomaly Face Syndrome

Digeorge Syndrome

Sedlackova Syndrome

Shprintzen Syndrome

Velocardiofacial Syndrome

22q11.2 Distal Deletion Syndrome

Distal 22q11.2 Microdeletion Syndrome

22q11.2ds

Vcfs

Velo-Cardio-Facial Syndrome

Distal Chromosome 22q11.2 Deletion Syndrome

Chromosome 22q11.2 Deletion Syndrome Distal

Chromosome 22q11.2 Deletion Syndrome

Deletion 22q11.2 Syndrome

22q11ds

Catch 22

Digeorge Sequence

Microdeletion 22q11.2

Monosomy 22q11

Takao Syndrome

Distal Del(22)(Q11.2)

Distal Monosomy 22q11.2

Catch 22 Syndrome

Chromosome Deletion Syndrome 22q11.2, Distal

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus CPLX3 VGNC VGNC:27653
Macaca mulatta CPLX3 VGNC VGNC:84328
Mus musculus CPLX3 MGD MGI:2384571
Canis familiaris CPLX3 VGNC VGNC:39557
Felis catus CPLX3 VGNC VGNC:61124
Rattus norvegicus CPLX3 RGD RGD:1560104
Others CPLX3 NCBI