2. Gene
  3. Msln - mesothelin Gene

Msln - mesothelin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 60333 | Gene type: protein coding

About Msln

Summary

Involved in pancreas development. Located in cell surface and extracellular space. Human ortholog(s) of this gene implicated in ovarian cancer; pancreas disease; pancreatic cancer; and pancreatic ductal carcinoma. Orthologous to human MSLN (Mesothelin). [provided by Alliance of Genome Resources, Apr 2022]

Msln Products(1)

mRNA Protein Name
NM_031658.1 NP_113846.1 mesothelin precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in pancreas development IEP
IEP: Inferred from expression pattern
18505465 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
18294289 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
18294289 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mesothelin

ERC/mesothelin

pre-pro-megakaryocyte-potentiating factor

protein expressed in renal carcinoma

Related Agents

Clinical Phase
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99006 Amatuximab Inhibitor 99.90% Phase 2
HY-P99352 Anetumab Inhibitor 98.78% Phase 2
Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08719 MSLN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-171269 Anetumab-MMAE / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99663 Inezetamab Inhibitor 99.77% Unkown
HY-P990929 Misitatug / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Msln NCBI NCBI:10232
Macaca fascicularis Msln NCBI NCBI:102130460
Mus musculus Msln NCBI NCBI:56047