2. Gene
  3. Kitlg - KIT ligand Gene

Kitlg - KIT ligand Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Mgf; SCF; Kitl

Gene ID: 60427 | Gene type: protein coding

About Kitlg

Summary

Predicted to enable cytokine activity and stem cell factor receptor binding activity. Involved in ovarian follicle development and positive regulation of cell population proliferation. Predicted to be located in several cellular components, including extracellular space; filopodium; and lamellipodium. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 69 and familial progressive hyperpigmentation with or without hypopigmentation. Orthologous to human KITLG (KIT ligand). [provided by Alliance of Genome Resources, Apr 2022]

Kitlg Products(2)

mRNA Protein Name
NM_021843.4 NP_068615.1 kit ligand isoform 1 precursor
NM_021844.2 NP_068616.1 kit ligand isoform 2 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in ovarian follicle development IDA
IDA: Inferred from direct assay
15062541 RGD
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
2208279 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
22777679 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kit ligand

C-kit ligand

hematopoietic growth factor KL

mast cell growth factor

steel factor/kit ligand

stem cell factor KL-1

Recombinant Kitlg Proteins

Cat. No. Product Name Accession Purity
HY-P7107 SCF Protein, Rat (P.pastoris) P21581-1 (Q26-A189) ≥95%
HY-P7107A SCF Protein, Rat (HEK293) P21581-1 (Q26-A189) ≥95%
HY-P71130 SCF Protein, Rat (HEK293, His) P21581-1 (Q26-A189) ≥95%
HY-P72480 SCF Protein, Rat (His) P21581-1 (Q26-A189) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07322 KITLG Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kitlg NCBI NCBI:4254
Canis familiaris Kitlg NCBI NCBI:403507
Mus musculus Kitlg NCBI