Angptl8 - angiopoietin-like 8 Gene

Mus musculus

Also known as Rifl; Gm6484; EG624219

Gene ID: 624219 | Gene type: protein coding

About Angptl8

Summary

Predicted to enable hormone activity. Involved in several processes, including regulation of lipid metabolic process; regulation of lipoprotein metabolic process; and triglyceride homeostasis. Acts upstream of or within cell maturation and fat cell differentiation. Predicted to be active in extracellular region. Orthologous to human ANGPTL8 (angiopoietin like 8). [provided by Alliance of Genome Resources, Apr 2022]

Angptl8 Products(1)

mRNA	Protein	Name
NM_001080940.1	NP_001074409.1	angiopoietin-like protein 8 precursor

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cell maturation	IMP IMP: Inferred from mutant phenotype	22569073	MGI
involved in cellular lipid metabolic process	IMP IMP: Inferred from mutant phenotype	22809513	MGI
acts upstream of or within fat cell differentiation	IMP IMP: Inferred from mutant phenotype	22569073	MGI
involved in fat cell differentiation	IMP IMP: Inferred from mutant phenotype	24043787	MGI
NOT involved in glucose metabolic process	IMP IMP: Inferred from mutant phenotype	24043787	MGI
acts upstream of or within regulation of lipid metabolic process	IMP IMP: Inferred from mutant phenotype	22569073	MGI
involved in regulation of lipid metabolic process	IMP IMP: Inferred from mutant phenotype	24043787	MGI
involved in regulation of lipoprotein metabolic process	IMP IMP: Inferred from mutant phenotype	24043787	MGI
involved in triglyceride homeostasis	IMP IMP: Inferred from mutant phenotype	22809513	MGI
NOT involved in type B pancreatic cell proliferation	IDA IDA: Inferred from direct assay	24353178	MGI
NOT involved in type B pancreatic cell proliferation	IMP IMP: Inferred from mutant phenotype	25417115	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

angiopoietin-like protein 8

betatrophin	hepatocellular carcinoma-associated protein TD26 homolog
lipasin	refeeding-induced fat and liver protein

Recombinant Angptl8 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P700561	ANGPTL8/Angiopoietin-like 8 Protein, Mouse (P. pastoris, His)	Q8R1L8 (V16-A198)	≥95%
HY-P700633	ANGPTL8/Angiopoietin-like 8 Protein, Mouse (H40A, Q44A, Q47A, His)	Q8R1L8 (V16-A198, H40A, Q44A, Q47A)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00697	ANGPTL8 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990336	Anti-ANGPTL8 Antibody		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Angptl8	NCBI	NCBI:55908

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