TSPAN31 - tetraspanin 31 Gene

Homo sapiens

Also known as SAS

Gene ID: 6302 | Gene type: protein coding

About TSPAN31

Cytogenetic location: 12q14.1 Genomic coordinates (GRCh38): 12:57,745,039-57,750,219 (from NCBI)

This gene has 14 transcripts (splice variants), 201 orthologues and 32 paralogues. Ubiquitous expression in thyroid (RPKM 18.9), adrenal (RPKM 13.0) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008]

TSPAN31 Products(3)

mRNA	Protein	Name
NM_001330168.2	NP_001317097.1	tetraspanin-31 isoform 2
NM_001330169.2	NP_001317098.1	tetraspanin-31 isoform 3 precursor
NM_005981.5	NP_005972.1	tetraspanin-31 isoform 1

TSPAN31 Protein Structure

Tetraspannin

0
100
210 a.a.

Protein Preferred Names

Protein Names

tetraspanin-31

sarcoma-amplified sequence

Recombinant TSPAN31 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76686	TSPAN31 Protein, Human (HEK293, Fc)	Q12999 (C94-K173)	≥95%

Related Diseases

Diseases

Alias

Breast Liposarcoma

Liposarcoma Of The Breast

Childhood Liposarcoma

Pediatric Liposarcoma

Well-Differentiated Liposarcoma

Atypical Lipomatous Tumor	Atypical Lipoma
Alt	Wdls
Liposarcoma, Well Differentiated	Pleomorphic Lipoma

Soft Tissue Chondroma

Extraskeletal Chondroma

Liposarcoma

Lipomatous Cancer

Sarcoma

Connective And Soft Tissue Neoplasm	Tumor Of Soft Tissue And Skeleton
Sarcomas	Sarcoma - Category

Pleomorphic Liposarcoma

Pls	Liposarcoma Pleomorphic
Liposarcoma, Pleomorphic

Diffuse Lipomatosis

Embryonal Rhabdomyosarcoma

Rhabdomyosarcoma, Embryonal	Rhabdomyosarcoma Embryonal
Botryoid Rhabdomyosarcoma	Erms
Spindle Cell Rhabdomyosarcomas

Retroperitoneal Sarcoma

Dedifferentiated Liposarcoma

Ddls	Liposarcoma Dedifferentiated
Liposarcoma, Dedifferentiated

Peripheral Osteosarcoma

Surface Osteosarcoma

Bone Surface Osteosarcoma

Cellular Myxoid Liposarcoma

Round Cell Liposarcoma

Anaplastic Astrocytoma

Grade Iii Astrocytoma	Astrocytoma, Anaplastic
Grade Iii Astrocytic Tumor

Lipomatosis, Multiple

Lipoma	Familial Multiple Lipomatosis
Lipomatosis, Familial Multiple	Benign Lipomatous Tumor
Lipomatous Neoplasm	Multiple Lipomatosis
Fml	Lipo
Benign Tumor Of Adipose Tissue	Lipomatous Tumor
Tumor Of Adipose Tissue	Neoplasms, Adipose Tissue
Lipomas

Familial Retinoblastoma

Hereditary Retinoblastoma

Retinoblastoma

Myxoid Liposarcoma

Myxoid/Round Cell Liposarcoma	Liposarcoma, Myxoid
Mrcls	Myxoliposarcoma
MXLIPO	Liposarcoma Myxoid
Liposarcoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15167	TSPAN31 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TSPAN31	MGD	MGI:1914375
Bos taurus	TSPAN31	VGNC	VGNC:36437
Canis familiaris	TSPAN31	VGNC	VGNC:47920
Macaca mulatta	TSPAN31	VGNC	VGNC:78552
Rattus norvegicus	TSPAN31	RGD	RGD:1309876
Felis catus	TSPAN31	VGNC	VGNC:66631
Others	TSPAN31	NCBI

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