LIPK - lipase family member K Gene

Homo sapiens

Also known as LIPL2; bA186O14.2

Gene ID: 643414 | Gene type: protein coding

About LIPK

Cytogenetic location: 10q23.31 Genomic coordinates (GRCh38): 10:88,706,249-88,752,776 (from NCBI)

This gene has 1 transcript (splice variant), 153 orthologues and 5 paralogues. Restricted expression toward skin (RPKM 5.3).

Summary

Predicted to enable lipoprotein Lipase activity. Predicted to be involved in cornification. Predicted to be located in extracellular region. Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

LIPK Products(2)

mRNA	Protein	Name
NM_001080518.2	NP_001073987.1	lipase member K isoform 1 precursor
NM_001378091.1	NP_001365020.1	lipase member K isoform 2 precursor

LIPK Protein Structure

Abhydro_lipase

Abhydrolase_1

0
100
200
300
399 a.a.

Protein Preferred Names

Protein Names

lipase member K

lipase K

Related Diseases

Diseases

Alias

Supratentorial Meningioma

Lipid Pneumonia

Exogenous Lipoid Pneumonia	Lipoid Pneumonitis
Pneumonia, Lipid	Pneumonia Lipid
Lipoid Pneumonia

Lysosomal Acid Lipase Deficiency

Wolman Disease	Cholesteryl Ester Storage Disease
Lal Deficiency	Lipa Deficiency
Cholesterol Ester Storage Disease	CESD
Cholesterol Ester Hydrolase Deficiency	Acid Lipase Deficiency
Acid Esterase Deficiency	Familial Xanthomatosis
Wolman Xanthomatosis	Wolman'S Disease
Wolman'S Or Triglyceride Storage Type Iii Disease	Xanthomatosis, Familial
Liposomal Acid Lipase Deficiency, Wolman Type	Familial Visceral Xanthomatosis
Primary Familial Xanthomatosis	Primary Familial Xanthomatosis With Adrenal Calcification
Acid Lipase Disease	WOD
Acid Cholesteryl Ester Hydrolase Deficiency, Type 2

Lysosomal And Lipase Deficiency

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07693	LIPK Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	LIPK	MGD	MGI:2679259
Felis catus	LIPK	VGNC	VGNC:63242
Bos taurus	LIPK	VGNC	VGNC:30907
Canis familiaris	LIPK	VGNC	VGNC:52938
Rattus norvegicus	LIPK	RGD	RGD:1309724
Macaca mulatta	LIPK	VGNC	VGNC:74341

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