2. Gene
  3. POLR1E - RNA polymerase I subunit E Gene

POLR1E - RNA polymerase I subunit E Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as A49; PAF53; PRAF1; RPA49

Gene ID: 64425 | Gene type: protein coding

About POLR1E

This gene has 3 transcripts (splice variants) and 201 orthologues. Ubiquitous expression in ovary (RPKM 15.6), endometrium (RPKM 8.0) and 25 other tissues.

Summary

Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and RNA polymerase I general transcription initiation factor binding activity. Involved in nucleolar large rRNA transcription by RNA polymerase I. Located in fibrillar center and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

POLR1E Products(2)

mRNA Protein Name
NM_001282766.2 NP_001269695.1 DNA-directed RNA polymerase I subunit RPA49 isoform 2
NM_022490.4 NP_071935.1 DNA-directed RNA polymerase I subunit RPA49 isoform 1

POLR1E Protein Structure

RNA_pol_I_A49

RNA_pol_I_A49: A49-like RNA polymerase I associated factor (97 - 475)

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  • 481 a.a.
Protein Preferred Names Protein Names

DNA-directed RNA polymerase I subunit RPA49

DNA-directed RNA polymerase I subunit E

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10841 POLR1E Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus POLR1E RGD RGD:1565773
Macaca mulatta POLR1E VGNC VGNC:76047
Felis catus POLR1E VGNC VGNC:64288
Mus musculus POLR1E MGD MGI:1929022
Canis familiaris POLR1E VGNC VGNC:44791
Bos taurus POLR1E VGNC VGNC:33134