Ntsr2 - neurotensin receptor 2 Gene

Rattus norvegicus

Gene ID: 64636 | Gene type: protein coding

About Ntsr2

Primary_assembly 6: 39,424,324-39,431,014 forward strand.mRatBN7.2:CM026979.1

This gene has 2 transcripts (splice variants), 79 orthologues, 14 paralogues and is associated with 1 phenotype. Restricted expression toward (RPKM 7.4).

Summary

Enables identical protein binding activity. Involved in positive regulation of ERK1 and ERK2 cascade. Located in several cellular components, including dendritic shaft; perikaryon; and trans-Golgi network. Orthologous to human NTSR2 (Neurotensin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ntsr2 Products(1)

mRNA	Protein	Name
NM_022695.2	NP_073186.1	neurotensin receptor type 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	17188644	RGD
enables protein-containing complex binding	IPI IPI: Inferred from physical interaction	17188644	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of ERK1 and ERK2 cascade	IDA IDA: Inferred from direct assay	16564027	RGD
involved in positive regulation of MAPK cascade	IDA IDA: Inferred from direct assay	12084713	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell surface	IDA IDA: Inferred from direct assay	16564027	RGD
located in dendritic shaft	IDA IDA: Inferred from direct assay	16564027	RGD
located in perikaryon	IDA IDA: Inferred from direct assay	16564027	RGD
located in trans-Golgi network	IDA IDA: Inferred from direct assay	16564027	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Ntsr2 Protein Structure

7tm_GPCRs

0
100
200
300
416 a.a.

Protein Preferred Names

Protein Names

neurotensin receptor type 2

NT-R-2	NTR2 receptor
high-affinity levocabastine-sensitive neurotensin receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09641	NTSR2 Human Pre-designed siRNA Set A		/	Unkown
HY-RS09642	Ntsr2 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS09643	Ntsr2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ntsr2	NCBI	NCBI:23620

Name
Email *

	Sorry, but the email address you supplied was invalid.