1. Gene
  2. FNDC4 - fibronectin type III domain containing 4 Gene

FNDC4 - fibronectin type III domain containing 4 Gene

Homo sapiens

Also known as FRCP1

Gene ID: 64838 | Gene type: protein coding

About FNDC4

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,491,883-27,495,200 (from NCBI)

This gene has 3 transcripts (splice variants), 152 orthologues and 1 paralogue. Biased expression in adrenal (RPKM 35.7), brain (RPKM 13.1) and 11 other tissues.

Summary

Involved in response to transforming growth factor beta. Predicted to be located in endoplasmic reticulum and extracellular space. Predicted to be active in extracellular region and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

FNDC4 Products(1)

mRNA Protein Name
NM_022823.3 NP_073734.1 fibronectin type III domain-containing protein 4 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to transforming growth factor beta IEP
IEP: Inferred from expression pattern
27066907 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FNDC4 Protein Structure

fn3

fn3: Fibronectin type III domain (48 - 129)

  • 0
  • 100
  • 200
  • 234 a.a.
Protein Preferred Names Protein Names

fibronectin type III domain-containing protein 4

fibronectin type III repeat-containing protein 1

Recombinant FNDC4 Proteins

Cat. No. Product Name Accession Purity
HY-P76935 FNDC4 Protein, Human (HEK293, Fc) Q9H6D8/NP_073734.1 (D45-T167) ≥95%

Related Diseases

Diseases Alias
Colitis
Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta FNDC4 VGNC VGNC:72538
Felis catus FNDC4 VGNC VGNC:62321
Rattus norvegicus FNDC4 RGD RGD:6496095
Bos taurus FNDC4 VGNC VGNC:29064
Canis familiaris FNDC4 VGNC VGNC:40930
Mus musculus FNDC4 MGD MGI:1917195
Others FNDC4 NCBI