1. Gene
  2. SLC6A4 - solute carrier family 6 member 4 Gene

SLC6A4 - solute carrier family 6 member 4 Gene

Homo sapiens

Also known as HTT; 5HTT; OCD1; SERT; 5-HTT; SERT1; hSERT; 5-HTTLPR

Gene ID: 6532 | Gene type: protein coding

About SLC6A4

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:30,194,319-30,235,697 (from NCBI)

This gene has 6 transcripts (splice variants), 204 orthologues, 19 paralogues and is associated with 2 phenotypes. Biased expression in lung (RPKM 18.0), small intestine (RPKM 13.9) and 3 other tissues.

Summary

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake. There have been conflicting results in the literature about the possible effect, if any, that this polymorphism may play in behavior and depression. [provided by RefSeq, May 2019]

SLC6A4 Products(1)

mRNA Protein Name
NM_001045.6 NP_001036.1 sodium-dependent serotonin transporter
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables antiporter activity IDA
IDA: Inferred from direct assay
27756841 GOA
enables integrin binding IDA
IDA: Inferred from direct assay
18317590 GOA
enables monoamine transmembrane transporter activity IDA
IDA: Inferred from direct assay
16024787 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
11343649 GOA
enables serotonin binding IDA
IDA: Inferred from direct assay
34851672 GOA
enables serotonin:sodium:chloride symporter activity IDA
IDA: Inferred from direct assay
8987735 GOA
enables serotonin:sodium:chloride symporter activity IMP
IMP: Inferred from mutant phenotype
12869649 GOA
enables sodium ion binding IDA
IDA: Inferred from direct assay
34851672 GOA
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within monoamine transport IDA
IDA: Inferred from direct assay
16024787 GOA
involved in regulation of thalamus size IMP
IMP: Inferred from mutant phenotype
18378990 GOA
involved in response to toxic substance IDA
IDA: Inferred from direct assay
17575980 GOA
involved in serotonin uptake IDA
IDA: Inferred from direct assay
8987735 GOA
involved in serotonin uptake IMP
IMP: Inferred from mutant phenotype
7681602 GOA
Cellular Component GO Annotation Evidence Reference Source
located in endomembrane system IDA
IDA: Inferred from direct assay
17506858 GOA
located in membrane raft IDA
IDA: Inferred from direct assay
16870614 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
12869649 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC6A4 Protein Structure

5HT_transport_N

5HT_transport_N: Serotonin (5-HT) neurotransmitter transporter, N-terminus (23 - 64)

SNF

SNF: Sodium:neurotransmitter symporter family (79 - 598)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 630 a.a.
Protein Preferred Names Protein Names

sodium-dependent serotonin transporter

5-hydroxytryptamine (serotonin) transporter

5HT transporter

Na+/Cl- dependent serotonin transporter

serotonin transporter 1

solute carrier family 6 (neurotransmitter transporter), member 4

solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Related Diseases

Diseases Alias
Amusia

Receptive Amusia

Somatization Disorder

Somatoform Disorders

Briquet'S Disorder

Polysomatising Disorder

Somatisation Disorder

Somatoform Disorder

Coronary Thrombosis

Coronary Artery Thrombosis

Exhibitionism
Gilles De La Tourette Syndrome

Tourette Syndrome

Tourette Disorder

GTS

Ts

Gilles De La Tourette'S Syndrome

Motor-Verbal Tic Disorder

Guinon'S Disease

Psychogenic Tics

Tourette'S Syndrome

Chronic Motor And Vocal Tic Disorder

Td

Tourette'S Disease

Combined Vocal And Multiple Motor Tic Disorder [De La Tourette]

Combined Vocal And Multiple Motor Tic Disorder

Tic De La Tourette

Plantar Fascial Fibromatosis

Dupuytren'S Contracture Of Foot

Ledderhose'S Disease

Fibromatosis, Plantar

Ledderhose Disease

Migraine With Aura

Classic Migraine

Migraine With Typical Aura

Migraine Accompagnée

Complicated Migraine

Classical Migraine

Acute Migraine With Aura

Paine Syndrome

Pain Disorder

Pain

Microcephaly With Spastic Diplegia

Pain Syndrome

Pedophilia

Paedophilia

Psychotic Disorder

Psychotic Disorders

Mental Or Behavioural Disorder

Psychotic

Mental Disorders

Acute Stress Disorder

Traumatic Stress Disorder

Stress Disorders, Traumatic, Acute

Stress Disorders, Traumatic

Cannabis Abuse

Marijuana Abuse

Intermittent Explosive Disorder

Explosive Personality Disorder

Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

Substance Abuse

Substance-Related Disorders

Substance Abuse Problem

Bruxism

Sleep Bruxism

Sleep-Related Bruxism

Bruxism - Teeth Grinding

Grinding Teeth

Sleep Related Bruxism

Teeth Grinding

Sleep Related Teeth Grinding

Tic Disorder

Tics

Behavioral Tic

Brunner Syndrome

Monoamine Oxidase A Deficiency

Antisocial Behavior

BRNRS

Deficiency Of Monoamine Oxidase A

X-Linked Monoamine Oxidase Deficiency

Susceptibility To Antisocial Behavior

Antisocial Behavior, Susceptibility To

Anti-Social Behavior

Trigeminal Neuralgia

Tic Douloureux

Trifacial Neuralgia

Trifocal Neuralgia

Neuralgia Of The Fifth Cranial Nerve

Neuralgia Of 5th Cranial Nerve

Infraorbital Neuralgia

Diarrhea

Diarrhoea

Diarrhea Of Presumed Infectious Origin

Hypertryptophanemia

HYPTRP

Hypertryptophanemia, Familial

Familial Hypertryptophanemia

Adjustment Disorder

Adjustment Reaction

Adjustment Disorders

Adjustment Disease

Brief Situational Non-Psychotic Disorder

Adaptation Reaction Nos

Emotional Crisis

Situational Disorder

Situational Disturbance

Situational Maladjustment

Situational Reaction

Situational Reaction With Maladjustment

Transient Situational Disturbance

Drug Dependence
Endogenous Depression

Clinical Depression

Unipolar Depression

Depressive Disorder

Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic

Inhibited Male Orgasm

Male Orgasmic Disorder

Psychosexual Dysfunction With Male Orgasmic Disorder

Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified

Panic Disorder

Panic Anxiety Syndrome

Panic

Panic Disorder 1

Episodic Paroxysmal Anxiety Disorder

Cyclothymic Disorder

Cyclothymia

Cycloid Personality

Cyclothymic Personality

Affective Personality Disorder

Cyclothymic Personality Disorder

Cycloid Personality Disorder

Trichotillomania

TTM

Hair-Pulling Syndrome

Compulsive Hair Plucking

Hair Pulling Disorder

Eating Disorder

Eating Disorders

Feeding And Eating Disorders

Atypical Depressive Disorder

Atypical Depression

Paraphilia Disorder

Paraphilia

Paraphilias

Alcohol Use Disorder

Alcohol Abuse

Alcoholism

Ethanol Abuse

Alcohol Addiction

Alcohol Dependence

Alcoholic Intoxication, Chronic

Alcohol-Related Disorders

Glossitis

Inflammation Of Tongue

Tongue Inflammation

Glazed Tongue

Conduct Disorder
Kleptomania

Pathological Stealing

Psychosexual Disorder

Psychosexual Disorders

Borderline Personality Disorder
Separation Anxiety Disorder

Separation Anxiety Disorder Of Childhood

Obsessive-Compulsive Disorder

OCD

Obsessive-Compulsive Disorder, Susceptibility To

Anancastic Neurosis

Obsessive Compulsive Disorder

Anankastic Neurosis

Obsessive-Compulsive Neurosis

Obsessive Compulsive Behavior

Placental Choriocarcinoma

Choriocarcinoma Of The Placenta

Constipation
Paranoid Schizophrenia

Chronic Paranoid Schizophrenia

Paranoid Type Schizophrenia

Paranoid Type Schizophrenia Subchronic State

Paraphrenia - Late

Paraphrenic Schizophrenia

Schizophrenia, Paranoid

Asperger Syndrome

Asperger Disorder

Impulse Control Disorder

Disruptive, Impulse Control, And Conduct Disorders

Patulous Eustachian Tube

Pet

Cocaine Abuse

Cocaine-Related Disorders

Chronic Fatigue Syndrome

Myalgic Encephalomyelitis

Postviral Fatigue Syndrome

Cfs

Myalgic Encephalitis

Encephalomyelitis, Myalgic

Chronic Fatigue

Fatigue Syndrome, Chronic

Benign Myalgic Encephalomyelitis

Akureyri

Akureyri Disease

Cfs - [Chronic Fatigue Syndrome]

Epidemic Neuromyasthenia

Myalgic Encephalomyelitis Syndrome

Me - [Myalgic Encephalomyelitis]

Pvfs - [Postviral Fatigue Syndrome]

Neuromyasthenia

Iceland Disease

Icelandic Disease

Central Nervous System Disease

CNS

Cns Diseases

Central Nervous System Diseases

Cns Disorder

Sleep Apnea

Sleep Apnea Syndromes

Frontotemporal Dementia

Pallidopontonigral Degeneration

Frontotemporal Lobar Degeneration

Semantic Dementia

FTD

Frontotemporal Lobe Dementia

Multiple System Tauopathy With Presenile Dementia

Dementia, Frontotemporal

Frontotemporal Dementia With Parkinsonism

Mstd

Frontotemporal Lobar Degeneration With Tau Inclusions

Ftld With Tau Inclusions

Dementia, Frontotemporal, With Parkinsonism

Fldem

Ftdp17

Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex

Ddpac

Wilhelmsen-Lynch Disease

Wld

Ppnd

Dementia, Frontotemporal, With Or Without Parkinsonism

Semantic Primary Progressive Aphasia

Semantic Variant Ppa

Wilhemsen-Lynch Disease

Frontotemporal Dementia-Amyotrophic Lateral Sclerosis

Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17

Ftd-Als

Ftld

Pick Complex

Pick Disease Of The Brain

Frontotemporal Dementia With Parkinsonism-17

Grn-Related Frontotemporal Dementia

Frontotemporal Dementia With Motor Neuron Disease

Dementia In Fronto-Temporal Lobar Degeneration

Ftd - [Frontotemporal Dementia]

Temple Dementia

Frontal Lobe Dementia

Alcohol Dependence

Alcoholism

Alcohol Dependence, Susceptibility To

Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against

Alcohol Dependence, Protection Against

Alcoholism, Susceptibility To

Alcoholic Intoxication, Chronic

Pharyngeal Neoplasms

Chronic Alcoholism

Dipsomania

Alcohol Addiction

Ethanol Dependence

Chronic Ethanolism

Chronic Alcoholic Disease Nos

Alcoholic Disease Nos

Alcoholic

Cascade Stomach

Hourglass Stricture Or Stenosis Of Stomach

Hourglass Contraction Of Stomach

Hourglass Stenosis Of Stomach

Hourglass Stricture Of Stomach

Migraine With Or Without Aura 1

Migraine

Migraine With Or Without Aura, Susceptibility To, 1

Migraine Disorder

Migraine Variant

Migraines

Migraine Disorders

Mgr1

Mgau

Ma

Migraine With Or Without Aura

Classic Migraine

Common Migraine

Disorder, Migraine

Headache Migraine

Headache Migrainous

Migraine Headache

Migraine Syndrome

Headache Including Migraine

Migraine, Susceptibility To

Obsessive-Compulsive Personality Disorder

Anankastic Personality Disorder

Obsessive-Compulsive Personality

Compulsive Personality Disorder

Ocpd

Obsessional Personality Disorder

Hypochondriasis

Hypochondriacal Disorder

Hypochondria

Hypochondriacal Neurosis

Illness Anxiety Disorder

Health Anxiety Disorder

Hypochondriacal Reaction

Dissociative Disorder

Dissociative Disorders

Dissociative Disease

Dissociative Reaction

Congenital Central Hypoventilation Syndrome

Cchs

Haddad Syndrome

Ondine Curse

Ondine Syndrome

Congenital Central Hypoventilation

Congenital Central Alveolar Hypoventilation Syndrome

Congenital Failure Of Autonomic Control

Ondine'S Curse

Primary Alveolar Hypoventilation

Ondine-Hirschsprung Disease

Central Congenital Hypoventilation Syndrome

Congenital Ondine Curse

Idiopathic Congenital Central Alveolar Hypoventilation

Congenital Central Alveolar Hypoventilation-Hirschsprung Disease Syndrome

Ondine-Hirschsprung Syndrome

Melancholia
Heroin Dependence
Oppositional Defiant Disorder

Disorder

Oppositional Defiance

Behavioural Disorder

Oppositional Defiance

Disruptive Mood Dysregulation Disorder

Serotonin Syndrome

Serotonergic Syndrome

Serotonin Storm

Serotonin Toxicity

Serotonin Toxidrome

Malignant Carcinoid Syndrome

Restless Legs Syndrome

Wed

Willis-Ekbom Disease

Restless Leg Syndrome

Ekbom Syndrome

Wittmaack-Ekbom Syndrome

Willis Ekbom Disease

Ekbom'S Syndrome

Rls

Restless Legs

Restless Legs Syndrome, Susceptibility To

Major Depressive Disorder

Seasonal Affective Disorder

Unipolar Depression

Depression

MDD

Depressive Disorder

Unipolar Depression, Susceptibility To

Major Depressive Disorder 1

Major Depressive Disorder, Response To Citalopram Therapy In

Major Depressive Disorder 2

Winter Depression

Single Major Depressive Episode

Sad

Clinical Depression

Major Depression

Depressive Syndrome

Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment

Seasonal Affective Disorder, Susceptibility To

Recurrent Major Depression

Affective Disorder, Seasonal

Depression In A Seasonal Pattern

Depression

Seasonal

Major Depressive Disorder With A Seasonal Pattern

Seasonal Depression

Seasonal Mood Disorder

Mental Depression

Recurrent Major Depressive Episodes

Fibromyalgia

Diffuse Myofascial Pain Syndrome

Fibromyalgia Syndrome

Fibromyalgia-Fibromyositis Syndrome

Fibromyositis

Fibrositis

Fms

Myofascial Pain Syndrome

Myofascial Pain Syndromes

Bipolar Disorder

Bipolar Depression

Manic Disorder

Depression, Bipolar

Bipolar Disorder Manic Phase

Depressive-Manic Psych.

Manic Bipolar Affective Disorder

Manic Bipolar I Disorder

Manic Depression

Manic Depressive Disorder

Mixed Bipolar Disorder

Bipolar Affective Disorder

Bipolar Affective Psychosis

Bipolar Spectrum Disorder

Manic Depressive Illness

Depression Bipolar

Bipolar Disorder, Mixed

Major Affective Disorder

Major Affective Disorder 1

Major Affective Disorder 2

Anorexia Nervosa

Anorexia Nervosa, Susceptibility To

ANON

Anorexia Nervosa, Susceptibility To, 1

An

Anorexia Nervosa 1

An - [Anorexia Nervosa]

Microphthalmia, Syndromic 13

X-Linked Colobomatous Microphthalmia-Microcephaly-Intellectual Disability-Short Stature Syndrome

MCOPS13

Maine Microphthalmos

Colobomatous Microphthalmia With Microcephaly, Short Stature, And Psychomotor Retardation

Syndromic Microphthalmia 13

X-Linked Colobomatous Microphthalmia-Microcephaly-Short Stature-Psychomotor Retardation Syndrome

Microphthalmia, Syndromic, 13

Microphthalmia, Syndromic, Type 13

Bulimia Nervosa

Bulimia

Bulimia Nervosa, Susceptibility To

Binge Eating Disorder

BULN

Bn

Hyperorexia Nervosa

Bulimia Nervosa 2

BULN2

Susceptibility To Bulimia Nervosa

Bulimia Nervosa, Susceptibility To, Type 2

Bn - [Bulimia Nervosa]

Bulimia Nos

Bulimic

Bingeing

Binge Overeating

Bouts Of Overeating

Episodes Of Overeating

Pervasive Developmental Disorder

Pervasive Development Disorder

Pervasive Developmental Disorders

Pervasive Child Development Disorders

Autistic Behavior

Autism Spectrum Disorders

Tobacco Addiction

Nicotine Dependence

Tobacco Addiction, Susceptibility To

Nicotine Addiction

Tobacco Use Disorder

Smoking Habit

Nicotine Dependence, Protection Against

Nicotine Addiction, Protection From

Cigarette Habituation

Cigarette Habituation, Susceptibility To

Smoking Habit, Susceptibility To

Nicotine Dependence, Susceptibility To

Nicotine Addiction, Susceptibility To

Addiction, Tobacco, Susceptibility To

Compulsive Tobacco User Syndrome

Tobacco Dependence

Tobacco Dependence Syndrome

Cigarette Addiction

Cigarette Dependence

Smoking Addiction

Smokers Syndrome

Irritable Bowel Syndrome

Irritable Colon

Psychogenic Ibs

Ibs - [Irritable Bowel Syndrome]

Spastic Bowel Syndrome

Kluver-Bucy Syndrome

Bilateral Temporal Lobe Disorder

Klüver-Bucy Syndrome

Klver-Bucy Syndrome

Kluver Bucy Syndrome

Memory Loss, Extreme Sexual Behavior, Placidity, And Visual Distractibility

Post-Encephalitic Kluver Bucy Syndrome

Post-Traumatic Kluver Bucy Syndrome

Cocaine Dependence
Headache

Headache Disorder

Leukodystrophy

Leukodystrophies

Mental Depression

Depression

Depressive Disorder

Animal Phobia

Zoophobia

Fear Of Animals

Substance Dependence
Pathological Gambling

Compulsive Gambling

Gambling

Gambling, Pathological

Addiction

Betting

Addiction

Gambling

Betting

Pathological

Gambling

Dependence

Social Phobia

Phobia, Social

Phobia Social

Phobic Anxiety Disorder

Personality Disorder

Personality Disorders

Character Disorder

Personality

Specific Personality Disorders

Enduring Personality Change After Psychiatric Illness

Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity

Burning Mouth Syndrome

Orodynia

Stomatodynia

Stomatopyrosis

Bms

Burning Mouth Disorder

Oral Dysesthesia

Sore Mouth Syndrome

Bms - [Burning Mouth Syndrome]

Fragile X Syndrome

FXS

Martin-Bell Syndrome

Fraxa Syndrome

Marker X Syndrome

X-Linked Mental Retardation And Macroorchidism

Fragile X Mental Retardation Syndrome

Fra Syndrome

Mental Retardation, X-Linked, Associated With Marxq28

Frax Syndrome

Symptomatic Form Of Fragile X Syndrome In Female Carriers

Fragile-X Syndrome

Fraxe Syndrome

Agoraphobia

Fear Of Open Spaces

Phobia Of Going Out

Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease

Dysthymic Disorder

Dysthymia

Chronic Depressive Disorder

Chronic Depression

Depressive Personality

Depressive Personality Disorder

Persistent Depressive Disorder

Persistent Depression

Specific Developmental Disorder
Pulmonary Hypertension

Primary Pulmonary Hypertension

Hypertension Pulmonary

Hypertension, Pulmonary

Idiopathic Pulmonary Hypertension

Idiopathic Pulmonary Arterial Hypertension

Pulmonary Htn - [Hypertension]

Fallopian Tube Clear Cell Adenocarcinoma

Clear Cell Carcinoma Of The Fallopian Tube

Mood Disorder

Mood Disorders

Episodic Mood Disorder

Disease Of Mental Health

Mental Health

Mental Disorders

Alcoholic Psychosis

Psychoses, Alcoholic

Alcoholic Psychoses

Outlet Dysfunction Constipation
Sexual Health Disorder

Sexual Health

Choriocarcinoma

Chorioepithelioma

Schizoaffective Disorder

Schizo-Affective Psychosis

Schizo-Affective Type Schizophrenia

Schizoaffective Psychosis

Schizoaffective Schizophrenia

Schizophrenia, Schizo-Affective Type

Schizophreniform Psychosis, Affective Type

Alcohol-Induced Mental Disorder

Psychoses, Alcoholic

Somatoform Disorder

Physiological Malfunction Arising From Mental Factor

Psychosomatic Disorder

Psychophysiologic Disorders

Bipolar I Disorder

Manic Depression Nos

Manic-Depressive Illness

Bipolar Disorder Nos

Antisocial Personality Disorder

Dissocial Personality Disorder

Asocial Personality

Psychopath.Personality

Psychopathic Personality

Psychopathic Personality Disorder

Sociopathic Personality

Generalized Anxiety Disorder

Anxiety Generalized

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers

Postpartum Depression

Maternity Blues

Postnatal Depression

Depression, Postpartum

Post-Partum Depression

Depression Postpartum

Anxiety

Anxiety Disorder

Anxiety Disorders

Anxiety State

Anxieties

Anxiety Neurosis

Post-Traumatic Stress Disorder

PTSD

Traumatic Neurosis

Post Traumatic Stress Disorder

Stress Disorders, Post-Traumatic

Posttraumatic Stress Disorder

Ptsd - [Post Traumatic Stress Disorder]

Trauma-Related Disorders

Avoidant Personality Disorder

Anxious Personality Disorder

Personality Disorders

Chronic Pulmonary Heart Disease
Sleep Disorder

Sleep Disorders

Non-Organic Sleep Disorder

Pyromania

Firesetting Behavior

Pathological Firesetting

Pathological Fire-Setting

Body Dysmorphic Disorder

Dysmorphophobia

Body Dysmorphia

Dysmorphic Syndrome

Body Dysmorphic Disorders

Amphetamine Abuse
Neurotic Disorder

Neurosis

Reactive Depression

Adjustment Disorders

Neurotic Disorders

Depressive Neurosis

Neurotic Depression

Neurotic Depression Reactive Type

Neurotic Depressive State

Psychoneurosis

Depressive Disorder

Depression, Neurotic

Gestational Choriocarcinoma

Gestational Chorionepithelioma

Molar Pregnancy With Choriocarcinoma

Premature Ejaculation
Gastroparesis

Gastroparesis Syndrome

Delayed Gastric Emptying

Gastric Atonia

Gastroparalysis

Phobia, Specific

Specific Phobia

Simple Phobia

Phobia, Simple

Isolated Phobia

Sudden Infant Death Syndrome

SIDS

Sudden Infant Death Syndrome, Susceptibility To

Cot Death

Crib Death

Sudden Death Of Nonspecific Cause In Infancy

Sudden Infant Death

Death, Sudden, Syndrome, Infant

Myocardial Infarction

Heart Attack

Myocardial Infarction, Susceptibility To

Myocardial Infarction 1

Myocardial Infarction, Protection Against

Myocardial Infarction, Decreased Susceptibility To

Myocardial Infarction, Decreased

Myocardial Infarct

MCI1

Premature Myocardial Infarction

Myocardial Infarction, Susceptibility To, Type 1

Retrograde Amnesia

Amnesia, Retrograde

Phobic Disorder

Phobic Disorders

Phobic Anxiety Disorder

Opiate Dependence

Opioid Dependence

Opioid Addiction

Opiate Addiction

Opioid Type Dependence

Opioid-Related Disorders

Opium Dependence

Narcotic Dependence

Intravenous Narcotism

Narcotism Nos

Oral Narcotism Nos

Migraine Without Aura

Common Migraine

Migraine With Or Without Aura, Susceptibility To

Migraine Without Aura, Susceptibility To

Acute Migraine Without Aura

Alexithymia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus SLC6A4 VGNC VGNC:49971
Felis catus SLC6A4 VGNC VGNC:65416
Rattus norvegicus SLC6A4 RGD RGD:3714
Macaca mulatta SLC6A4 VGNC VGNC:77620
Mus musculus SLC6A4 MGD MGI:96285
Canis familiaris SLC6A4 VGNC VGNC:46465