2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor Serotonin Transporter
  4. Zimelidine dihydrochloride

Zimelidine dihydrochloride is a potent and selective inhibitor of serotonin 5-HT uptake and SERT. Zimelidine dihydrochloride is an antidepressant.

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Zimelidine dihydrochloride Chemical Structure

Zimelidine dihydrochloride Chemical Structure

CAS No. : 60525-15-7

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5 mg USD 280 In-stock
10 mg USD 450 In-stock
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50 mg USD 1440 In-stock
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Other Forms of Zimelidine dihydrochloride:

Zimelidine dihydrochloride Related Antibodies

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Description

Zimelidine dihydrochloride is a potent and selective inhibitor of serotonin 5-HT uptake and SERT. Zimelidine dihydrochloride is an antidepressant[1].

Molecular Weight

390.15

Formula

C16H19BrCl2N2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN(C/C=C(C1=CC=CN=C1)/C2=CC=C(C=C2)Br)C.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (320.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5631 mL 12.8156 mL 25.6312 mL
5 mM 0.5126 mL 2.5631 mL 5.1262 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5631 mL 12.8156 mL 25.6312 mL 64.0779 mL
5 mM 0.5126 mL 2.5631 mL 5.1262 mL 12.8156 mL
10 mM 0.2563 mL 1.2816 mL 2.5631 mL 6.4078 mL
15 mM 0.1709 mL 0.8544 mL 1.7087 mL 4.2719 mL
20 mM 0.1282 mL 0.6408 mL 1.2816 mL 3.2039 mL
25 mM 0.1025 mL 0.5126 mL 1.0252 mL 2.5631 mL
30 mM 0.0854 mL 0.4272 mL 0.8544 mL 2.1359 mL
40 mM 0.0641 mL 0.3204 mL 0.6408 mL 1.6019 mL
50 mM 0.0513 mL 0.2563 mL 0.5126 mL 1.2816 mL
60 mM 0.0427 mL 0.2136 mL 0.4272 mL 1.0680 mL
80 mM 0.0320 mL 0.1602 mL 0.3204 mL 0.8010 mL
100 mM 0.0256 mL 0.1282 mL 0.2563 mL 0.6408 mL
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Zimelidine dihydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zimelidine60525-15-75-HT ReceptorSerotonin TransporterSerotonin Receptor5-hydroxytryptamine Receptor5-HTTSERTSLC6A4antidepressantserotonin reuptakeneurotransmissionInhibitorinhibitorinhibit

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