SURF2 - surfeit 2 Gene

Homo sapiens

Also known as SURF-2

Gene ID: 6835 | Gene type: protein coding

About SURF2

Cytogenetic location: 9q34.2 Genomic coordinates (GRCh38): 9:133,356,550-133,361,158 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele and 120 orthologues. Broad expression in testis (RPKM 30.3), kidney (RPKM 8.2) and 25 other tissues.

Summary

This gene shares a bidirectional promoter with surfeit 1 (SURF1; GeneID: 6834), which is located on the opposite strand. It encodes a conserved protein that is expressed in a variety of tissues. [provided by RefSeq, Jul 2013]

SURF2 Products(2)

mRNA	Protein	Name
NM_001278928.2	NP_001265857.1	surfeit locus protein 2 isoform 2
NM_017503.5	NP_059973.4	surfeit locus protein 2 isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21900206	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SURF2 Protein Structure

SURF2

0
100
200
256 a.a.

Protein Preferred Names

Protein Names

surfeit locus protein 2

SURF2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SURF2	Q15527	RPL5	Homo sapiens	P46777	Anti Tag CoIP	28514442
Intra	SURF2	Q15527	RPL5	Homo sapiens	P46777	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Hypotonia-Cystinuria Syndrome

Cystinuria With Mitochondrial Disease	2p21 Microdeletion Syndrome
HCS	Homozygous 2p16 Deletion Syndrome, Formerly
2p21 Deletion Syndrome	Del(2)(P21)
Monosomy 2p21	Atypical Hypotonia-Cystinuria Syndrome
Atypical Hcs

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14043	SURF2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SURF2	MGD	MGI:98444
Macaca mulatta	SURF2	VGNC	VGNC:78059
Rattus norvegicus	SURF2	RGD	RGD:1565817
Bos taurus	SURF2	VGNC	VGNC:35484
Canis familiaris	SURF2	VGNC	VGNC:46995
Felis catus	SURF2	VGNC	VGNC:102989

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