2. Gene
  3. Usp46 - ubiquitin specific peptidase 46 Gene

Usp46 - ubiquitin specific peptidase 46 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 1190009E20Rik; 2410018I08Rik

Gene ID: 69727 | Gene type: protein coding

About Usp46

Summary

Enables Deubiquitinase activity. Involved in regulation of GABAergic synaptic transmission. Acts upstream of or within several processes, including adult feeding behavior; behavioral fear response; and behavioral response to ethanol. Predicted to be active in cytosol and nucleus. Is expressed in pancreas epithelium. Orthologous to human USP46 (ubiquitin specific peptidase 46). [provided by Alliance of Genome Resources, Apr 2022]

Usp46 Products(1)

mRNA Protein Name
NM_177561.3 NP_808229.1 ubiquitin carboxyl-terminal hydrolase 46
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables deubiquitinase activity IDA
IDA: Inferred from direct assay
26811477 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within adult feeding behavior IMP
IMP: Inferred from mutant phenotype
23472206 MGI
acts upstream of or within behavioral fear response IMP
IMP: Inferred from mutant phenotype
22720038 MGI
acts upstream of or within behavioral response to ethanol IMP
IMP: Inferred from mutant phenotype
23472206 MGI
acts upstream of or within protein deubiquitination IDA
IDA: Inferred from direct assay
26811477 MGI
involved in regulation of synaptic transmission, GABAergic IMP
IMP: Inferred from mutant phenotype
19465912 MGI
acts upstream of or within righting reflex IMP
IMP: Inferred from mutant phenotype
23472206 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 46

deubiquitinating enzyme 46

ubiquitin specific protease 46

ubiquitin thioesterase 46

ubiquitin thiolesterase 46

ubiquitin-specific-processing protease 46

Recombinant Usp46 Proteins

Cat. No. Product Name Accession Purity
HY-P77277 USP46 Protein, Human/Mouse (sf9) P62069 (M1-E366) ≥95%
HY-P77278 USP46 Protein, Human/Mouse (sf9, SUMO) P62069 (M1-E366) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15557 USP46 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp46 NCBI NCBI:64854