2. Gene
  3. Pla2g12b - phospholipase A2, group XIIB Gene

Pla2g12b - phospholipase A2, group XIIB Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Fksg71; hlb218; Pla2g13; 2010002E04Rik

Gene ID: 69836 | Gene type: protein coding

About Pla2g12b

Summary

Predicted to enable calcium ion binding activity and Phospholipase A2 activity. Acts upstream of or within Cholesterol homeostasis; low-density lipoprotein particle remodeling; and triglyceride homeostasis. Predicted to be located in extracellular region. Is expressed in alimentary system; liver; liver lobe; and yolk sac endoderm. Orthologous to human PLA2G12B (Phospholipase A2 group XIIB). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g12b Products(1)

mRNA Protein Name
NM_023530.2 NP_076019.2 group XIIB secretory phospholipase A2-like protein precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cholesterol homeostasis IMP
IMP: Inferred from mutant phenotype
22912808 MGI
acts upstream of or within low-density lipoprotein particle remodeling IDA
IDA: Inferred from direct assay
27471003 MGI
acts upstream of or within triglyceride homeostasis IMP
IMP: Inferred from mutant phenotype
22912808 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

group XIIB secretory phospholipase A2-like protein

GXIIB

group XIIB phospholipase A2

group XIII secretory phospholipase A2-like protein

phospholipase A2, group XIII

sPLA2-GXIIB

Recombinant Pla2g12b Proteins

Cat. No. Product Name Accession Purity
HY-P77144 PLA2G12B Protein, Mouse (HEK293, His) Q8VC81 (Q20-L195) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10618 PLA2G12B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2g12b NCBI NCBI:84647