Cysltr2 - cysteinyl leukotriene receptor 2 Gene

Mus musculus

Also known as Cltr2; Cyslt2; CYSLT2R; 2300001H05Rik

Gene ID: 70086 | Gene type: protein coding

About Cysltr2

Chromosome 14: 73,263,043-73,286,554 reverse strand.GRCm39:CM001007.3

This gene has 5 transcripts (splice variants), 55 orthologues, 13 paralogues and is associated with 18 phenotypes. Broad expression in thymus adult (RPKM 1.4), spleen adult (RPKM .4) and 17 other tissues.

Summary

Enables cysteinyl Leukotriene Receptor activity. Predicted to be involved in several processes, including neuropeptide signaling pathway; positive regulation of ERK1 and ERK2 cascade; and positive regulation of angiogenesis. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Located in membrane. Human ortholog(s) of this gene implicated in aspirin-induced respiratory disease and asthma. Orthologous to human CYSLTR2 (cysteinyl Leukotriene Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Cysltr2 Products(2)

mRNA	Protein	Name
NM_001162412.2	NP_001155884.1	cysteinyl leukotriene receptor 2
NM_133720.4	NP_598481.2	cysteinyl leukotriene receptor 2

Cysltr2 Protein Structure

7tm_GPCRs

0
100
200
309 a.a.

Protein Preferred Names

Protein Names

cysteinyl leukotriene receptor 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03497	CYSLTR2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS03498	Cysltr2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS03499	Cysltr2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cysltr2	NCBI	NCBI:57105

Name
Email *

	Sorry, but the email address you supplied was invalid.