2. Gene
  3. FAM72A - family with sequence similarity 72 member A Gene

FAM72A - family with sequence similarity 72 member A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as p17; LMPIP; Ugene

Gene ID: 729533 | Gene type: protein coding

About FAM72A

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:206,186,179-206,205,773 (from NCBI)

This gene has 8 transcripts (splice variants), 196 orthologues and 3 paralogues. Broad expression in lymph node (RPKM 5.1), bone marrow (RPKM 2.8) and 17 other tissues.

Summary

Predicted to act upstream of or within negative regulation of brain-derived neurotrophic factor-activated receptor activity and positive regulation of apoptotic process. Located in cytosol and intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

FAM72A Products(11)

mRNA Protein Name
NM_001123168.3 NP_001116640.1 protein FAM72A isoform 1
NM_001317901.2 NP_001304830.1 protein FAM72A isoform 2
NM_001385240.1 NP_001372169.1 protein FAM72A isoform 1
NM_001385241.1 NP_001372170.1 protein FAM72A isoform 1
NM_001385242.1 NP_001372171.1 protein FAM72A isoform 1
NM_001385243.1 NP_001372172.1 protein FAM72A isoform 2
NM_001385244.1 NP_001372173.1 protein FAM72A isoform 2
NM_001385245.1 NP_001372174.1 protein FAM72A isoform 2
NM_001385248.1 NP_001372177.1 protein FAM72A isoform 3
NM_001385249.1 NP_001372178.1 protein FAM72A isoform 3
NM_001385251.1 NP_001372180.1 protein FAM72A isoform 4
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FAM72A Protein Structure

FAM72

FAM72: FAM72 protein (1 - 149)

  • 0
  • 100
  • 149 a.a.
Protein Preferred Names Protein Names

protein FAM72A

LMP1-induced protein

FAM72A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
FAM72A Q5TYM5 MPPED2 Homo sapiens Q15777
Y2H Array
25416956
Intra
FAM72A Q5TYM5 MPPED2 Homo sapiens Q15777
Y2H Prey Pooling
25416956
Intra
FAM72A Q5TYM5 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04718 FAM72A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus FAM72A MGD MGI:1919669
Rattus norvegicus FAM72A RGD RGD:1598023