2. Gene
  3. Robo4 - roundabout guidance receptor 4 Gene

Robo4 - roundabout guidance receptor 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 1200012D01Rik

Gene ID: 74144 | Gene type: protein coding

About Robo4

Summary

Enables signaling receptor activity. Acts upstream of or within negative regulation of cell migration. Located in external side of plasma membrane. Is expressed in several structures, including forebrain; genitourinary system; neural retina; submandibular gland; and vascular system. Human ortholog(s) of this gene implicated in aortic valve disease 3. Orthologous to human ROBO4 (roundabout guidance receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Robo4 Products(2)

mRNA Protein Name
NM_001309390.2 NP_001296319.2 roundabout homolog 4 isoform 1 precursor
NM_028783.4 NP_083059.3 roundabout homolog 4 isoform 2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12941633 MGI
enables signaling receptor activity IDA
IDA: Inferred from direct assay
12941633 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of blood vessel endothelial cell migration IDA
IDA: Inferred from direct assay
12941633 MGI
acts upstream of or within negative regulation of blood vessel endothelial cell migration IDA
IDA: Inferred from direct assay
12941633 MGI
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
12941633 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

roundabout homolog 4

Magic roundabout

Recombinant Robo4 Proteins

Cat. No. Product Name Accession Purity
HY-P78031 ROBO4 Protein, Mouse (HEK293, His) Q8C310-1 (L28-W480) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12113 ROBO4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Robo4 NCBI NCBI:54538