2. Gene
  3. Manf - mesencephalic astrocyte-derived neurotrophic factor Gene

Manf - mesencephalic astrocyte-derived neurotrophic factor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Armet; D18Mgi17; 3230402M22Rik

Gene ID: 74840 | Gene type: protein coding

About Manf

Summary

Predicted to enable sulfatide binding activity. Acts upstream of or within vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure. Predicted to be located in endoplasmic reticulum lumen and perinuclear region of cytoplasm. Predicted to be active in endoplasmic reticulum and extracellular space. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in Parkinsonism; breast cancer; carcinoma (multiple); and pancreatic Cancer. Orthologous to human MANF (mesencephalic astrocyte derived neurotrophic factor). [provided by Alliance of Genome Resources, Apr 2022]

Manf Products(1)

mRNA Protein Name
NM_029103.4 NP_083379.2 mesencephalic astrocyte-derived neurotrophic factor precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure IDA
IDA: Inferred from direct assay
18718866 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mesencephalic astrocyte-derived neurotrophic factor

arginine-rich protein

arginine-rich, mutated in early stage tumors

Recombinant Manf Proteins

Cat. No. Product Name Accession Purity
HY-P77296 ARMET/MANF Protein, Mouse (HEK293, His) Q9CXI5/NP_083379.2 (L22-L179) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08017 MANF Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Manf NCBI NCBI:7873