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Results for "

7695

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Natural
Products

2

Recombinant Proteins

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N7695
    Physalin B

    		Apoptosis Autophagy Cancer
    Physalin B, one of the major active steroidal constituents of Cape gooseberry, induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. Physalin B inhibits the ubiquitin-proteasome pathway and induces incomplete autophagic response in human colon cancer cells in vitro .
    Physalin B
  • HY-R02416
    hsa-miR-769-5p mimic

    		MicroRNA Cancer
    hsa-miR-769-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-769-5p mimic
    hsa-miR-769-5p mimic
  • HY-RI02416
    hsa-miR-769-5p inhibitor

    		MicroRNA Cancer
    hsa-miR-769-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-769-5p inhibitor
    hsa-miR-769-5p inhibitor
  • HY-R02416A
    hsa-miR-769-5p agomir

    		MicroRNA Cancer
    hsa-miR-769-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-769-5p agomir
    hsa-miR-769-5p agomir
  • HY-163211
    SARS-CoV-2 Mpro-IN-14

    		SARS-CoV Infection
    SARS-CoV-2 Mpro-IN-14 (Compound 19) is an inhibitor of SARS-CoV-2 Mpro with an IC50 of 0.044 μM. SARS-CoV-2 Mpro-IN-14 exhibits water solubility, has no cytotoxicity, and can be used in the study of COVID-19 .
    SARS-CoV-2 Mpro-IN-14
  • HY-RI02416A
    hsa-miR-769-5p antagomir

    		MicroRNA Cancer
    hsa-miR-769-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-769-5p antagomir
    hsa-miR-769-5p antagomir

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