2. Gene
  3. PVRIG - PVR related immunoglobulin domain containing Gene

PVRIG - PVR related immunoglobulin domain containing Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CD112R; C7orf15

Gene ID: 79037 | Gene type: protein coding

About PVRIG

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,219,248-100,221,490 (from NCBI)

This gene has 3 transcripts (splice variants) and 71 orthologues. Broad expression in lymph node (RPKM 13.9), spleen (RPKM 12.7) and 25 other tissues.

Summary

Enables Phosphatase binding activity and signaling receptor activity. Involved in negative regulation of T cell receptor signaling pathway. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

PVRIG Products(3)

mRNA Protein Name
NM_001387134.1 NP_001374063.1 transmembrane protein PVRIG isoform 2 precursor
NM_001397246.1 NP_001384175.1 transmembrane protein PVRIG isoform 3 precursor
NM_024070.3 NP_076975.2 transmembrane protein PVRIG isoform 1
Protein Preferred Names Protein Names

transmembrane protein PVRIG

CD112 receptor

Recombinant PVRIG Proteins

Cat. No. Product Name Accession Purity
HY-P71247 PVRIG Protein, Human (HEK293, Fc) Q6DKI7 (T41-D171) ≥95%
HY-P71248 PVRIG Protein, Human (HEK293, mFc) Q6DKI7 (T41-D171) ≥95%
HY-P72409 PVRIG Protein, Human (Biotinylated, HEK293, Fc-Avi) Q6DKI7 (T41-D171) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11474 PVRIG Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus PVRIG MGD MGI:5596028
Rattus norvegicus PVRIG RGD RGD:1585866
Felis catus PVRIG VGNC VGNC:64441
Bos taurus PVRIG VGNC VGNC:49566
Macaca fascicularis PVRIG NCBI NCBI:102127364
Others PVRIG NCBI