PRKRIP1 - PRKR interacting protein 1 Gene

Homo sapiens

Also known as C114; KRBOX3

Gene ID: 79706 | Gene type: protein coding

About PRKRIP1

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:102,396,363-102,426,666 (from NCBI)

This gene has 8 transcripts (splice variants) and 197 orthologues. Ubiquitous expression in testis (RPKM 12.5), lymph node (RPKM 10.7) and 25 other tissues.

Summary

Predicted to enable double-stranded RNA binding activity; protein kinase binding activity; and protein kinase inhibitor activity. Involved in renal system process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PRKRIP1 Products(1)

mRNA	Protein	Name
NM_024653.4	NP_078929.1	PRKR-interacting protein 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in renal system process	IDA IDA: Inferred from direct assay	21183621	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRKRIP1 Protein Structure

DUF1168

0
100
184 a.a.

Protein Preferred Names

Protein Names

PRKR-interacting protein 1

KRAB box domain containing 3

PRKRIP1 Protein-protein interaction Information

Type Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PRKRIP1	Q9H875	TRAF2	Homo sapiens	Q12933	Y2H Prey Pooling	25416956
Intra	PRKRIP1	Q9H875	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	25416956
Intra	PRKRIP1	Q9H875	CEP70	Homo sapiens	Q8NHQ1	Validated Y2H	25416956
Intra	PRKRIP1	Q9H875	CEP70	Homo sapiens	Q8NHQ1	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Fructose-1,6-Bisphosphatase Deficiency

Fructose-1,6-Diphosphatase Deficiency	Baker-Winegrad Disease
FBP1D	Fbpase Deficiency
Fructose 1,6 Diphosphatase Deficiency	Fructose 1 Phosphate Aldolase Deficiency
Fbp1 Deficiency	Hereditary Fructose Intolerance Syndrome

Noonan Syndrome 6

NS6	Noonan Syndrome, Type 6

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect Pre-designed Sets	Purity	Rare Diseases Unkown
HY-RS11158	PRKRIP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PRKRIP1	RGD	RGD:1595708
Felis catus	PRKRIP1	VGNC	VGNC:64357
Mus musculus	PRKRIP1	MGD	MGI:1914051
Bos taurus	PRKRIP1	VGNC	VGNC:49564
Canis familiaris	PRKRIP1	VGNC	VGNC:49780

Name
Email *

	Sorry, but the email address you supplied was invalid.