2. Gene
  3. ZNF768 - zinc finger protein 768 Gene

ZNF768 - zinc finger protein 768 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 79724 | Gene type: protein coding

About ZNF768

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:30,524,004-30,532,477 (from NCBI)

This gene has 2 transcripts (splice variants), 91 orthologues and 51 paralogues. Ubiquitous expression in testis (RPKM 9.9), kidney (RPKM 9.1) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZNF768 Products(1)

mRNA Protein Name
NM_024671.4 NP_078947.3 zinc finger protein 768
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
30476274 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
30476274 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF768 Protein Structure

RNA_pol_Rpb1_R

RNA_pol_Rpb1_R: RNA polymerase Rpb1 C-terminal repeat (60 - 72)

RNA_pol_Rpb1_R

RNA_pol_Rpb1_R: RNA polymerase Rpb1 C-terminal repeat (117 - 128)

RNA_pol_Rpb1_R

RNA_pol_Rpb1_R: RNA polymerase Rpb1 C-terminal repeat (130 - 142)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (278 - 299)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (304 - 327)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (332 - 354)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (387 - 411)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (419 - 439)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (457 - 479)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (500 - 523)

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  • 540 a.a.
Protein Preferred Names Protein Names

zinc finger protein 768

ZNF768 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
ZNF768 Q9H5H4 RPS10 Homo sapiens P46783
Anti Tag CoIP
33961781
Intra
ZNF768 Q9H5H4 ZNF330 Homo sapiens Q9Y3S2
Validated Y2H
32296183
Intra
ZNF768 Q9H5H4 ZNF835 Homo sapiens Q9Y2P0
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16174 ZNF768 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ZNF768 VGNC VGNC:54099
Rattus norvegicus ZNF768 RGD RGD:7609558
Felis catus ZNF768 VGNC VGNC:107836
Macaca mulatta ZNF768 VGNC VGNC:82280
Mus musculus ZNF768 MGD MGI:2384582