APOL6 - apolipoprotein L6 Gene

Homo sapiens

Also known as APOLVI; APOL-VI

Gene ID: 80830 | Gene type: protein coding

About APOL6

Cytogenetic location: 22q12.3 Genomic coordinates (GRCh38): 22:35,648,446-35,668,404 (from NCBI)

This gene has 1 transcript (splice variant), 343 orthologues and 6 paralogues. Ubiquitous expression in fat (RPKM 14.3), liver (RPKM 13.1) and 24 other tissues.

Summary

This gene is a member of the Apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. [provided by RefSeq, Jul 2008]

APOL6 Products(1)

mRNA	Protein	Name
NM_030641.4	NP_085144.1	apolipoprotein L6

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

APOL6 Protein Structure

ApoL

0
100
200
300
343 a.a.

Protein Preferred Names

Protein Names

apolipoprotein L6

apolipoprotein L, 6

APOL6 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	APOL6	Q9BWW8	KRTAP10-8	Homo sapiens	P60410	Y2H Array	32296183
Intra	APOL6	Q9BWW8	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	32296183
Intra	APOL6	Q9BWW8	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Prey Pooling	32296183
Intra	APOL6	Q9BWW8	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Array	32296183
Intra	APOL6	Q9BWW8	LAMTOR3	Homo sapiens	Q9UHA4	Y2H Prey Pooling	32296183
Intra	APOL6	Q9BWW8	LAMTOR3	Homo sapiens	Q9UHA4	Validated Y2H	32296183
Intra	APOL6	Q9BWW8	LAMTOR3	Homo sapiens	Q9UHA4	Y2H Array	32296183
Intra	APOL6	Q9BWW8	TEPSIN	Homo sapiens	Q96N21	Y2H Array	32296183
Intra	APOL6	Q9BWW8	TEPSIN	Homo sapiens	Q96N21	Y2H Prey Pooling	32296183
Intra	APOL6	Q9BWW8	RGS13	Homo sapiens	O14921	Y2H Array	32296183
Intra	APOL6	Q9BWW8	RGS13	Homo sapiens	O14921	Y2H Prey Pooling	32296183
Intra	APOL6	Q9BWW8	GMCL1	Homo sapiens	Q96IK5	Y2H Prey Pooling	32296183
Intra	APOL6	Q9BWW8	GMCL1	Homo sapiens	Q96IK5	Y2H Array	32296183
Intra	APOL6	Q9BWW8	CCN3	Homo sapiens	P48745	Y2H Array	32296183
Intra	APOL6	Q9BWW8	CCN3	Homo sapiens	P48745	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00858	APOL6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	APOL6	VGNC	VGNC:82105
Mus musculus	APOL6	MGD	MGI:1919189
Canis familiaris	APOL6	VGNC	VGNC:38006

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