Cxcr6 - chemokine (C-X-C motif) receptor 6 Gene

Mus musculus

Also known as BONZO; STRL33

Gene ID: 80901 | Gene type: protein coding

About Cxcr6

Chromosome 9: 123,635,540-123,640,825 forward strand.GRCm39:CM001002.3

This gene has 2 transcripts (splice variants), 97 orthologues, 25 paralogues and is associated with 2 phenotypes. Biased expression in mammary gland adult (RPKM 2.4), spleen adult (RPKM 2.2) and 14 other tissues.

Summary

Enables C-X-C chemokine binding activity and C-X-C Chemokine Receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system and retina. Orthologous to human CXCR6 (C-X-C motif Chemokine Receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Cxcr6 Products(1)

mRNA	Protein	Name
NM_030712.4	NP_109637.3	C-X-C chemokine receptor type 6

Cxcr6 Protein Structure

7tmA_CXCR6

0
100
200
300
351 a.a.

Protein Preferred Names

Protein Names

C-X-C chemokine receptor type 6

CXC-R6

CXCR-6

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-122197	ML339	Antagonist	99.88%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cxcr6	NCBI	NCBI:10663

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