Apba2 - amyloid beta precursor protein binding family A member 2 Gene

Rattus norvegicus

Also known as Mint2

Gene ID: 83610 | Gene type: protein coding

About Apba2

Summary

Enables amyloid-beta binding activity. Predicted to be involved in chemical synaptic transmission and regulation of synaptic vesicle exocytosis. Predicted to act upstream of or within in utero embryonic development; locomotory behavior; and regulation of gene expression. Located in plasma membrane. Orthologous to human APBA2 (amyloid beta precursor protein binding family A member 2). [provided by Alliance of Genome Resources, Apr 2022]

Apba2 Products(1)

mRNA	Protein	Name
NM_031780.2	NP_113968.1	amyloid-beta A4 precursor protein-binding family A member 2

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables amyloid-beta binding	IPI IPI: Inferred from physical interaction	12196555	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	9395480	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in presynapse	IDA IDA: Inferred from direct assay	20369384	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

amyloid-beta A4 precursor protein-binding family A member 2

adapter protein X11beta	amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)
neuron-specific X11L protein	neuronal Munc18-1-interacting protein 2

Apba2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Apba2	O35431	Stxbp1	Rattus norvegicus	P61765	Anti Bait CoIP	9395480
Intra	Apba2	O35431	Stxbp1	Rattus norvegicus	P61765	Pull Down	9395480
Intra	Apba2	O35431	Tamalin	Rattus norvegicus	Q8R4T5	Anti Bait CoIP	12586822
Intra	Apba2	O35431	Tamalin	Rattus norvegicus	Q8R4T5	Pull Down	12586822
Cross	Apba2	O35431	APP	Homo sapiens	P05067	X-Ray Diffraction	22730553
Cross	Apba2	O35431	APP	Homo sapiens	P05067	Filter Binding	22730553

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00803	APBA2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Apba2	NCBI	NCBI:321

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