2. Gene
  3. RSPH3 - radial spoke head 3 Gene

RSPH3 - radial spoke head 3 Gene

  • Gene
  • Protein
Homo sapiens (human)

Also known as RSP3; RSHL2; CILD32; dJ111C20.1

Gene ID: 83861 | Gene type: protein coding

About RSPH3

Summary

The protein encoded by this gene acts as a protein kinase A anchoring protein. Mutations in this gene cause primary ciliary dyskinesia; a disorder characterized by defects of the axoneme in motile cilia and sperm flagella. The homolog of this gene was first identified in the Blue-green algae Chlamydomonas as encoding a radial spoke protein that formed a structural component of motile cilia and flagella. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]

RSPH3 Products(1)

mRNA Protein Name
XR_001743668.3
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cilium IDA
IDA: Inferred from direct assay
27120127 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

radial spoke head protein 3 homolog

A-kinase anchor protein RSPH3

radial spoke 3 homolog

radial spoke head 3 homolog

radial spoke head-like protein 2

RSPH3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra RSPH3 Q86UC2 FAM124B Homo sapiens Q9H5Z6-2
Validated Y2H
32296183
Intra RSPH3 Q86UC2 DPY30 Homo sapiens Q9C005
Validated Y2H
32296183
Intra RSPH3 Q86UC2 RSPH14 Homo sapiens Q9UHP6
Validated Y2H
32296183
Intra RSPH3 Q86UC2 ROPN1L Homo sapiens Q96C74
Y2H Prey Pooling
25416956
Intra RSPH3 Q86UC2 ROPN1L Homo sapiens Q96C74
Validated Y2H
25416956
Intra RSPH3 Q86UC2 ROPN1L Homo sapiens Q96C74
Validated Y2H
32296183
Intra RSPH3 Q86UC2 ROPN1L Homo sapiens Q96C74
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction