2. Gene
  3. Dll1 - delta like canonical Notch ligand 1 Gene

Dll1 - delta like canonical Notch ligand 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 84010 | Gene type: protein coding

About Dll1

Summary

Enables Notch binding activity. Involved in clathrin-dependent endocytosis and positive regulation of Notch signaling pathway. Predicted to be located in several cellular components, including adherens junction; apical plasma membrane; and membrane raft. Predicted to be active in plasma membrane. Orthologous to human DLL1 (delta like canonical Notch ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Dll1 Products(2)

mRNA Protein Name
NM_032063.3 NP_114452.2 delta-like protein 1 precursor
NM_032063.3 NP_114452.2 delta-like protein 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables Notch binding IPI
IPI: Inferred from physical interaction
10079256 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
22658936 RGD
Biological Process GO Annotation Evidence Reference Source
involved in clathrin-dependent endocytosis IDA
IDA: Inferred from direct assay
22658936 RGD
involved in positive regulation of Notch signaling pathway IDA
IDA: Inferred from direct assay
22658936 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

delta-like protein 1

delta1

drosophila Delta homolog 1

Recombinant Dll1 Proteins

Cat. No. Product Name Accession Purity
HY-P72971 Delta-like protein 1/DLL1 Protein, Rat (HEK293, Fc) EDL99825.1 (S22-S534) ≥95%
HY-P75295 Delta-like protein 1/DLL1 Protein, Rat (HEK293, His) P97677 (Q18-S534) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990077 Pidilizumab Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03808 DLL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dll1 NCBI NCBI:28514
Mus musculus Dll1 NCBI NCBI:13388