C7orf50 - chromosome 7 open reading frame 50 Gene

Homo sapiens

Also known as YCR016W

Gene ID: 84310 | Gene type: protein coding

About C7orf50

This gene has 8 transcripts (splice variants) and 172 orthologues. Ubiquitous expression in kidney (RPKM 5.2), brain (RPKM 3.9) and 25 other tissues.

Summary

Enables RNA binding activity. [provided by Alliance of Genome Resources, Apr 2022]

C7orf50 Products(7)

mRNA	Protein	Name
NM_001134395.1	NP_001127867.1	uncharacterized protein C7orf50 isoform a
NM_001134396.1	NP_001127868.1	uncharacterized protein C7orf50 isoform a
NM_001318252.2	NP_001305181.1	uncharacterized protein C7orf50 isoform a
NM_001350968.1	NP_001337897.1	uncharacterized protein C7orf50 isoform b
NM_001350969.2	NP_001337898.1	uncharacterized protein C7orf50 isoform c
NM_001350970.1	NP_001337899.1	uncharacterized protein C7orf50 isoform d
NM_032350.5	NP_115726.1	uncharacterized protein C7orf50 isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables hormone activity	IDA IDA: Inferred from direct assay	38503280	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of cholesterol biosynthetic process	IDA IDA: Inferred from direct assay	38503280	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
is active in extracellular space	IDA IDA: Inferred from direct assay	38503280	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C7orf50 Protein Structure

DUF2373

0
100
194 a.a.

Protein Preferred Names

Protein Names

uncharacterized protein C7orf50

C7orf50 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	C7orf50	Q9BRJ6	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
Intra	C7orf50	Q9BRJ6	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
Intra	C7orf50	Q9BRJ6	WFS1	Homo sapiens	O76024	Y2H Array	32814053
Intra	C7orf50	Q9BRJ6	THAP1	Homo sapiens	Q9NVV9	Y2H Prey Pooling	32296183
Intra	C7orf50	Q9BRJ6	THAP1	Homo sapiens	Q9NVV9	Validated Y2H	32296183
Intra	C7orf50	Q9BRJ6	THAP1	Homo sapiens	Q9NVV9	Y2H Array	25416956
Intra	C7orf50	Q9BRJ6	THAP1	Homo sapiens	Q9NVV9	Y2H Array	32296183
Intra	C7orf50	Q9BRJ6	THAP1	Homo sapiens	Q9NVV9	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Albinism, Oculocutaneous, Type V

OCA5	Oculocutaneous Albinism Type V
Oculocutaneous Albinism Type 5

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01754	C7orf50 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	C7orf50	VGNC	VGNC:70609
Felis catus	C7orf50	VGNC	VGNC:80558
Rattus norvegicus	C7orf50	RGD	RGD:1566418
Mus musculus	C7orf50	MGD	MGI:1920462
Bos taurus	C7orf50	VGNC	VGNC:54411
Canis familiaris	C7orf50	VGNC	VGNC:54009

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