2. Gene
  3. TUBA1C - tubulin alpha 1c Gene

TUBA1C - tubulin alpha 1c Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as TUBA6; bcm948

Gene ID: 84790 | Gene type: protein coding

About TUBA1C

This gene has 9 transcripts (splice variants), 174 orthologues and 23 paralogues. Ubiquitous expression in esophagus (RPKM 168.9), bone marrow (RPKM 156.4) and 25 other tissues.

Summary

Predicted to enable GTP binding activity. Predicted to be a structural constituent of Cytoskeleton. Predicted to be involved in microtubule Cytoskeleton organization and mitotic cell cycle. Located in microtubule Cytoskeleton and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

TUBA1C Products(5)

mRNA Protein Name
NM_001303114.1 NP_001290043.1 tubulin alpha-1C chain isoform a
NM_001303115.2 NP_001290044.1 tubulin alpha-1C chain isoform b
NM_001303116.2 NP_001290045.1 tubulin alpha-1C chain isoform b
NM_001303117.2 NP_001290046.1 tubulin alpha-1C chain isoform b
NM_032704.5 NP_116093.1 tubulin alpha-1C chain isoform c
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
22720776 GOA
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
22720776 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TUBA1C Protein Structure

Tubulin

Tubulin: Tubulin/FtsZ family, GTPase domain (3 - 225)

Tubulin_C

Tubulin_C: Tubulin C-terminal domain (263 - 392)

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  • 400
  • 449 a.a.
Protein Preferred Names Protein Names

tubulin alpha-1C chain

alpha-tubulin 6

TUBA1C Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
TUBA1C Q9BQE3 VIM Homo sapiens P08670
Y2H
27107012
Intra
TUBA1C Q9BQE3 VIM Homo sapiens P08670
BFG-2H
27107012
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15247 TUBA1C Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TUBA1C MGD MGI:1095409
Rattus norvegicus TUBA1C RGD RGD:1307226