ABHD14B - abhydrolase domain containing 14B Gene

Homo sapiens

Also known as CIB; HEL-S-299

Gene ID: 84836 | Gene type: protein coding

About ABHD14B

This gene has 8 transcripts (splice variants), 208 orthologues and 12 paralogues. Ubiquitous expression in fat (RPKM 33.8), kidney (RPKM 32.8) and 25 other tissues.

Summary

Enables hydrolase activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ABHD14B Products(3)

mRNA	Protein	Name
NM_001146314.2	NP_001139786.1	putative protein-lysine deacylase ABHD14B isoform 1
NM_001254753.1	NP_001241682.1	putative protein-lysine deacylase ABHD14B isoform 3
NM_032750.3	NP_116139.1	putative protein-lysine deacylase ABHD14B isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables hydrolase activity	IDA IDA: Inferred from direct assay	14672934	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	14672934	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	14672934	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytosol	IDA IDA: Inferred from direct assay	14672934	GOA
located in nucleus	IDA IDA: Inferred from direct assay	14672934	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ABHD14B Protein Structure

Abhydrolase_5

0
100
210 a.a.

Protein Preferred Names

Protein Names

putative protein-lysine deacylase ABHD14B

CCG1-interacting factor B

Recombinant ABHD14B Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76132	ABHD14B Protein, Human (His)	Q96IU4-1 (M1-Q210)	≥95%

Related Diseases

Diseases

Alias

Williams-Beuren Syndrome

Williams Syndrome	WBS
Wms	Deletion 7q11.23
Monosomy 7q11.23	Chromosome 7q11.23 Deletion Syndrome, 1.5- To 1.8-Mb
Fanconi Schlesinger Syndrome	Beuren Syndrome
Elfin Facies Syndrome	Elfin Facies With Hypercalcemia
Hypercalcemia-Supravalvar Aortic Stenosis	Ws

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00088	ABHD14B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ABHD14B	RGD	RGD:1359649
Bos taurus	ABHD14B	VGNC	VGNC:25493
Mus musculus	ABHD14B	MGD	MGI:1923741
Canis familiaris	ABHD14B	VGNC	VGNC:37462
Felis catus	ABHD14B	VGNC	VGNC:59479
Macaca mulatta	ABHD14B	VGNC	VGNC:69541
Others	ABHD14B	NCBI

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