RELT - RELT TNF receptor Gene

Homo sapiens

Also known as AI3C; TRLT; TNFRSF19L

Gene ID: 84957 | Gene type: protein coding

About RELT

Cytogenetic location: 11q13.4 Genomic coordinates (GRCh38): 11:73,376,399-73,397,474 (from NCBI)

This gene has 7 transcripts (splice variants), 197 orthologues, 21 paralogues and is associated with 2 phenotypes. Biased expression in bone marrow (RPKM 25.4), spleen (RPKM 6.1) and 8 other tissues.

Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

RELT Products(2)

mRNA	Protein	Name
NM_032871.4	NP_116260.2	tumor necrosis factor receptor superfamily member 19L precursor
NM_152222.2	NP_689408.1	tumor necrosis factor receptor superfamily member 19L precursor

RELT Protein Structure

RELT

0
100
200
300
400
430 a.a.

Protein Preferred Names

Protein Names

tumor necrosis factor receptor superfamily member 19L

RELT tumor necrosis factor receptor

Recombinant RELT Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71258	RELT Protein, Human (HEK293, Fc)	Q969Z4 (S26-A160)	≥95%

Related Diseases

Diseases

Alias

Amelogenesis Imperfecta, Type Iiic

AI3C	Amelogenesis Imperfecta, Hypocalcification Type, Autosomal Recessive
Amelogenesis Imperfecta Type 3c	Amelogenesis Imperfecta, Type 3c
Amelogenesis Imperfecta Type Iiic	Autosomal Recessive Amelogenesis Imperfecta Hypocalcification Type
Amelogenesis Imperfecta 3c

Hypoplastic Amelogenesis Imperfecta

Amelogenesis Imperfecta Type 1	Amelogenesis Imperfecta, Hypoplastic Type
Amelogenesis Imperfecta Local Hypoplastic Form

Amelogenesis Imperfecta

Ai	Congenital Enamel Hypoplasia
Al - [Amelogenesis Imperfecta]

Myopathy, Congenital, Compton-North

Compton-North Congenital Myopathy	MYPCN
Congenital Lethal Myopathy, Compton-North Type

Amelogenesis Imperfecta, Hypomaturation Type, Iia5

Amelogenesis Imperfecta Hypomaturation Type 2a5	AI2A5
Amelogenesis Imperfecta, Type Iia5	Amelogenesis Imperfecta Hypomaturation Type Iia5
Amelogenesis Imperfecta Type Iia5	Amelogenesis Imperfecta, Hypomaturation Type, 2a5

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11836	RELT Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	RELT	VGNC	VGNC:64568
Rattus norvegicus	RELT	RGD	RGD:1305381
Bos taurus	RELT	VGNC	VGNC:33862
Canis familiaris	RELT	VGNC	VGNC:45471
Mus musculus	RELT	MGD	MGI:2443373
Macaca mulatta	RELT	VGNC	VGNC:76728
Others	RELT	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.