2. Gene
  3. Plg - plasminogen Gene

Plg - plasminogen Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ab1-346

Gene ID: 85253 | Gene type: protein coding

About Plg

Summary

Enables endopeptidase activity and Enzyme binding activity. Involved in proteolysis involved in cellular protein catabolic process. Located in extracellular space; intracellular membrane-bounded organelle; and plasma membrane. Human ortholog(s) of this gene implicated in COVID-19; conjunctivitis; myocardial infarction; plasminogen deficiency type I; and thrombophilia. Orthologous to several human genes including PLG (plasminogen). [provided by Alliance of Genome Resources, Apr 2022]

Plg Products(1)

mRNA Protein Name
NM_053491.2 NP_445943.1 plasminogen precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables endopeptidase activity IDA
IDA: Inferred from direct assay
7864083 RGD
enables enzyme binding IPI
IPI: Inferred from physical interaction
7964722 RGD
Biological Process GO Annotation Evidence Reference Source
involved in proteolysis involved in protein catabolic process IDA
IDA: Inferred from direct assay
7864083 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
7964722 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

plasminogen

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103423 PAOPA Modulator 97.68% Unkown
HY-RS10704 PLG Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plg NCBI NCBI:5340
Canis familiaris Plg NCBI NCBI:403602
Macaca fascicularis Plg NCBI NCBI:102145643
Mus musculus Plg NCBI NCBI:18815
Macaca mulatta Plg NCBI NCBI:703891