YBX3 - Y-box binding protein 3 Gene

Homo sapiens

Also known as CSDA; DBPA; CSDA1; ZONAB

Gene ID: 8531 | Gene type: protein coding

About YBX3

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,699,089-10,723,323 (from NCBI)

This gene has 18 transcripts (splice variants), 131 orthologues and 4 paralogues. Broad expression in testis (RPKM 175.4), skin (RPKM 131.9) and 23 other tissues.

Summary

Enables RNA binding activity. Involved in cellular hyperosmotic response; cellular response to tumor necrosis factor; and negative regulation of programmed cell death. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

YBX3 Products(2)

mRNA	Protein	Name
NM_001145426.2	NP_001138898.1	Y-box-binding protein 3 isoform b
NM_003651.5	NP_003642.3	Y-box-binding protein 3 isoform a

YBX3 Protein Structure

CSD

0
100
200
300
372 a.a.

Protein Preferred Names

Protein Names

Y-box-binding protein 3

DNA-binding protein A

YBX3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	YBX3	P16989	UXT	Homo sapiens	Q9UBK9-2	Anti Tag CoIP	37608570

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Lyme Disease

Lyme Borreliosis	Lyme Neuroborreliosis
Borreliosis	Borrelia Burgdorferi Infection
Neuroborreliosis	Bannwarth Syndrome
Bannworth'S Syndrome	Neurological Lyme Disease
B. Burgdorferi Infection	Borreliosis, Lyme
Infection By Borrelia Burgdorferi	Infection Due To Borrelia Burgdorferi Sensu Lato
Lym	Borrelia Infections

Tick-Borne Relapsing Fever

Relapsing Fever, Tick-Borne	Relapsing Fever Due To Any Borrelia Species Other Than Borrelia Recurrentis
African Tick-Borne Fever

Tick Infestation

Tick Infestations

Acrodermatitis Chronica Atrophicans

Acrodermatitis Atrophicans Chronica	Herxheimer Disease
Primary Diffuse Atrophy

Relapsing Fever

Febris Recurrens	Novy Febris Recurrens
Novy Relapsing Fever

Bejel

Njovera	Dichuchwa
Nonvenereal Endemic Syphilis	Endemic Syphilis
Frenga	Nonvenereal Syphilis
Treponemal Infections	Non-Venereal Endemic Syphilis
Siti	Skerljevo
Belesh

Louse-Borne Relapsing Fever

Relapsing Fever, Louse-Borne

Relapsing Fever Due To Borrelia Recurrentis

Leukodystrophy, Hypomyelinating, 2

Pmld1	Hypomyelinating Leukodystrophy 2
HLD2	Pelizaeus-Merzbacher-Like Disease 1
Pelizaeus-Merzbacher-Like Disease Due To Gjc2 Mutation	Pelizaeus-Merzbacher-Like Disease Type 1
Pelizaeus-Merzbacher-Like Disease, 1	Pelizaeus Merzbacher Like Disease
Pelizaeus-Merzbacher-Like Disease	Pmld - Pelizaeus Merzbacher Like Disease
Pelizaeus-Merzbacher-Like Disease Autosomal Recessive Type 1	Pmldar1
Leukodystrophy, Hypomyelinating, Type 2

Parasitic Ectoparasitic Infectious Disease

Ectoparasitic Infestations

Ectoparasitism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15918	YBX3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	YBX3	VGNC	VGNC:37018
Felis catus	YBX3	VGNC	VGNC:67132
Canis familiaris	YBX3	VGNC	VGNC:48480
Mus musculus	YBX3	MGD	MGI:2137670
Rattus norvegicus	YBX3	RGD	RGD:621056
Macaca mulatta	YBX3	VGNC	VGNC:79428

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