CIPC - CLOCK interacting pacemaker Gene

Homo sapiens

Also known as KIAA1737

Gene ID: 85457 | Gene type: protein coding

About CIPC

Cytogenetic location: 14q24.3 Genomic coordinates (GRCh38): 14:77,098,258-77,117,287 (from NCBI)

This gene has 8 transcripts (splice variants) and 249 orthologues. Ubiquitous expression in brain (RPKM 21.3), heart (RPKM 15.0) and 25 other tissues.

Summary

Predicted to be involved in negative regulation of circadian rhythm and negative regulation of transcription, DNA-templated. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CIPC Products(1)

mRNA	Protein	Name
NM_033426.3	NP_219494.2	CLOCK-interacting pacemaker

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

CLOCK-interacting pacemaker

CLOCK-interacting circadian protein

CIPC Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CIPC	Q9C0C6	RABGEF1	Homo sapiens	Q9UJ41	Y2H Prey Pooling	25416956
Intra	CIPC	Q9C0C6	RABGEF1	Homo sapiens	Q9UJ41	Validated Y2H	25416956
Intra	CIPC	Q9C0C6	RABGEF1	Homo sapiens	Q9UJ41	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome 1

Eec Syndrome	Rudiger Syndrome 1
Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome 1	EEC1
Eec Syndrome 1	Eec Syndrome-1
Walker-Clodius Syndrome	Ectrodactyly-Ectodermal Dysplasia-Cleft Lip/Palate Syndrome
Eec	Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome
Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome	Ectrodactyly-Cleft Lip/Palate Syndrome
Ectrodactyly-Ectodermal Dysplasia-Cleft Lip/Cleft Palate	Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome
Ectrodactyly, Ectodermal Dysplasia, Clefting Syndrome	Ectrodactyly-Cleft Lip-Palate Syndrome
Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02719	CIPC Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CIPC	VGNC	VGNC:39278
Bos taurus	CIPC	VGNC	VGNC:27370
Felis catus	CIPC	VGNC	VGNC:104368
Mus musculus	CIPC	MGD	MGI:1919185
Rattus norvegicus	CIPC	RGD	RGD:1309492

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