LY6D - lymphocyte antigen 6 family member D Gene

Homo sapiens

Also known as E48; Ly-6D

Gene ID: 8581 | Gene type: protein coding

About LY6D

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:142,784,882-142,786,539 (from NCBI)

This gene has 4 transcripts (splice variants), 90 orthologues and 1 paralogue. Biased expression in esophagus (RPKM 212.7) and skin (RPKM 206.5).

Summary

Predicted to be involved in lymphocyte differentiation. Predicted to act upstream of or within response to stilbenoid. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in cell surface. [provided by Alliance of Genome Resources, Apr 2022]

LY6D Products(1)

mRNA	Protein	Name
NM_003695.3	NP_003686.1	lymphocyte antigen 6D precursor

LY6D Protein Structure

UPAR_LY6

0
100
128 a.a.

Protein Preferred Names

Protein Names

lymphocyte antigen 6D

e48 antigen

Related Diseases

Diseases

Alias

Inflammatory Bowel Disease 27

IBD27

Squamous Cell Carcinoma, Head And Neck

Squamous Cell Carcinoma Of The Head And Neck	HNSCC
Head And Neck Squamous Cell Carcinoma	Squamous Cell Carcinoma Of Lip
Squamous Cell Carcinoma, Head And Neck, Somatic	Carcinoma Of The Head And Neck
Squamous Cell Carcinomas Of Head And Neck	Scchn
Squamous Cell Carcinoma Of The Hypopharynx	Squamous Cell Carcinoma Of The Oropharynx
Squamous Cell Carcinoma Of Salivary Glands	Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses
Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses	Squamous Cell Carcinoma Of The Oral Cavity
Squamous Cell Carcinoma Of The Lip	Carcinoma, Squamous Cell Of Head And Neck
Lip Squamous Cell Carcinoma	Carcinoma, Squamous Cell, Head And Neck
Salivary Gland Squamous Cell Carcinoma	Cancer Of Head And Neck
Squamous Cell Carcinoma Of Oropharynx Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07896	LY6D Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	LY6D	VGNC	VGNC:42872
Bos taurus	LY6D	VGNC	VGNC:31088
Rattus norvegicus	LY6D	RGD	RGD:1306132
Mus musculus	LY6D	MGD	MGI:96881
Macaca mulatta	LY6D	VGNC	VGNC:104461
Others	LY6D	NCBI

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