2. Gene
  3. MIDN - midnolin Gene

MIDN - midnolin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as Stx

Gene ID: 90007 | Gene type: protein coding

About MIDN

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,248,583-1,259,143 (from NCBI)

This gene has 5 transcripts (splice variants) and 194 orthologues. Ubiquitous expression in bone marrow (RPKM 27.5), gall bladder (RPKM 18.8) and 25 other tissues.

Summary

Predicted to enable kinase binding activity. Predicted to be involved in negative regulation of Glucokinase activity and negative regulation of Insulin secretion. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

MIDN Products(4)

mRNA Protein Name
NM_001388306.1 NP_001375235.1 midnolin isoform 1
NM_001388307.1 NP_001375236.1 midnolin isoform 3
NM_001388474.1 NP_001375403.1 midnolin isoform 2
NM_177401.5 NP_796375.3 midnolin isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables molecular adaptor activity IDA
IDA: Inferred from direct assay
37616343 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence Reference Source
involved in proteasomal ubiquitin-independent protein catabolic process IDA
IDA: Inferred from direct assay
37616343 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
24187134 GOA
located in nucleus IDA
IDA: Inferred from direct assay
24187134 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MIDN Protein Structure

ubiquitin

ubiquitin: Ubiquitin family (40 - 99)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 468 a.a.
Protein Preferred Names Protein Names

midnolin

midbrain nucleolar protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08438 MIDN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MIDN RGD RGD:1309629
Canis familiaris MIDN VGNC VGNC:43225
Bos taurus MIDN VGNC VGNC:31466
Felis catus MIDN VGNC VGNC:102638
Mus musculus MIDN MGD MGI:1890222
Macaca mulatta MIDN VGNC VGNC:82186